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| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (432 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase. (535 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | DYRK1B | Dual specificity tyrosine phosphorylation regulated kinase 1B. (589 aa) |
| | E2F4 | E2F transcription factor 4. (418 aa) |
| | PSMC5 | Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa) |
| | PSMB10 | Proteasome subunit beta. (273 aa) |
| | PSMD8 | Proteasome 26S subunit, non-ATPase 8. (287 aa) |
| | PSMD12 | Proteasome 26S subunit, non-ATPase 12. (456 aa) |
| | PSMD7 | Proteasome 26S subunit, non-ATPase 7. (324 aa) |
| | LIN37 | Lin-37 DREAM MuvB core complex component. (246 aa) |
| | LIN54 | Lin-54 DREAM MuvB core complex component. (749 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa) |
| | PSMA1 | Proteasome subunit alpha type. (130 aa) |
| | CCNE1 | Cyclin E1; Belongs to the cyclin family. (416 aa) |
| | CDK3 | Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (314 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (420 aa) |
| | CDK2 | Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | UBA52 | Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa) |
| | FNBP4 | Formin binding protein 4. (1015 aa) |
| | PSMD11 | Proteasome 26S subunit, non-ATPase 11. (422 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa) |
| | CUL1 | Cullin 1; Belongs to the cullin family. (776 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | RRM2 | Ribonucleotide reductase regulatory subunit M2. (390 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (162 aa) |
| | E2F6 | E2F transcription factor 6. (281 aa) |
| | E2F3 | E2F_CC-MB domain-containing protein. (224 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa) |
| | GMNN | Geminin DNA replication inhibitor. (209 aa) |
| | WEE2 | Wee1-like protein kinase. (567 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (738 aa) |
| | DYRK1A | Dual specificity tyrosine phosphorylation regulated kinase 1A. (725 aa) |
| | TM4SF19 | Uncharacterized protein. (209 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | JAK2 | Tyrosine-protein kinase. (1130 aa) |
| | PSMD10 | Proteasome 26S subunit, non-ATPase 10. (226 aa) |
| | TESMIN | Testis expressed metallothionein like protein. (508 aa) |
| | ENSCSAP00000005289 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (398 aa) |
| | ENSCSAP00000005494 | ANK_REP_REGION domain-containing protein. (217 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa) |
| | PSMB8 | Proteasome subunit beta. (308 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | CDKN1C | Cyclin dependent kinase inhibitor 1C. (329 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (137 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | ENSCSAP00000006740 | Uncharacterized protein. (525 aa) |
| | ENSCSAP00000006748 | Uncharacterized protein. (550 aa) |
| | PSMF1 | Proteasome inhibitor subunit 1. (271 aa) |
| | ORC2 | Origin recognition complex subunit 2. (577 aa) |
| | PPP2R3A | Uncharacterized protein. (529 aa) |
| | PPP4R4 | Protein phosphatase 4 regulatory subunit 4. (872 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (289 aa) |
| | PSMD13 | Proteasome 26S subunit, non-ATPase 13. (377 aa) |
| | TFDP2 | Transcription factor. (404 aa) |
| | MEIOB | Meiosis specific with OB-fold. (472 aa) |
| | CCND3 | Cyclin D3; Belongs to the cyclin family. (292 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | CDC45 | Cell division cycle 45. (566 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa) |
| | PSMB1 | Proteasome subunit beta. (241 aa) |
| | PSMD6 | Proteasome 26S subunit, non-ATPase 6. (412 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (288 aa) |
| | E2F1 | E2F transcription factor 1. (437 aa) |
| | DBF4 | DBF4 zinc finger. (675 aa) |
| | POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (383 aa) |
| | LIN52 | Lin-52 DREAM MuvB core complex component. (84 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | FNDC3B | Fibronectin type III domain containing 3B. (1204 aa) |
| | PSMB6 | Proteasome subunit beta. (239 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (808 aa) |
| | RPA3 | Replication protein A3. (121 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (874 aa) |
| | E2F5 | E2F transcription factor 5. (351 aa) |
| | PSMD5 | Proteasome 26S subunit, non-ATPase 5. (504 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | MAX | MYC associated factor X. (103 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa) |
| | MCM8 | MCM domain-containing protein; Belongs to the MCM family. (840 aa) |
| | FBXO5 | F-box protein 5. (448 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | SKP1 | S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa) |
| | SRC | Tyrosine-protein kinase. (633 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa) |
| | MYBL2 | MYB proto-oncogene like 2. (700 aa) |
| | RPS27A | Ubiquitin-like domain-containing protein. (156 aa) |
| | MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) |
| | POLA1 | DNA polymerase. (1465 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | ABL1 | Tyrosine-protein kinase. (1130 aa) |
| | CCNH | Cyclin H; Belongs to the cyclin family. (323 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | PSMA4 | Proteasome subunit alpha type. (261 aa) |
| | PSMC6 | Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | PSMA6 | Proteasome subunit alpha type. (252 aa) |
| | LOC103243620 | WRNPLPNID domain-containing protein. (925 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (117 aa) |
| | PPP2CB | Serine/threonine-protein phosphatase. (309 aa) |
| | CDK7 | Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa) |
| | CCNB1 | Cyclin B1; Belongs to the cyclin family. (429 aa) |
| | CDC25A | Cell division cycle 25A. (523 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (447 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa) |
| | PSME2 | Proteasome activator subunit 2. (253 aa) |
| | PSMB5 | Proteasome subunit beta. (263 aa) |
| | PSME1 | Proteasome activator subunit 1. (238 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | LIN9 | Lin-9 DREAM MuvB core complex component. (490 aa) |
| | PTK6 | Tyrosine-protein kinase. (451 aa) |
| | SKP2 | S-phase kinase associated protein 2. (424 aa) |
| | ORC3 | Origin recognition complex subunit 3. (711 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | ENSCSAP00000013550 | PROTEASOME_ALPHA_1 domain-containing protein. (218 aa) |
| | PPP4R1 | Protein phosphatase 4 regulatory subunit 1. (933 aa) |
| | TYMS | Thymidylate synthetase. (313 aa) |
| | CABLES1 | Cdk5 and Abl enzyme substrate 1. (630 aa) |
| | FNDC3A | Fibronectin type III domain containing 3A. (1198 aa) |
| | RB1 | RB transcriptional corepressor 1. (928 aa) |
| | ENSCSAP00000013833 | Uncharacterized protein. (132 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa) |
| | CCNA1 | Cyclin A1; Belongs to the cyclin family. (465 aa) |
| | RELCH | RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa) |
| | PPP2R3B | EF-hand domain-containing protein. (575 aa) |
| | PSME3 | Proteasome activator subunit 3. (267 aa) |
| | ENSCSAP00000014778 | RPA_C domain-containing protein. (256 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (551 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (599 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa) |
| | PSMD3 | Proteasome 26S subunit, non-ATPase 3. (534 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | TK1 | Thymidine kinase. (276 aa) |
| | PSMD9 | PDZ domain-containing protein. (223 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (589 aa) |
| | UBC | Uncharacterized protein. (228 aa) |
| | ENSCSAP00000016053 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa) |
| | PSMB4 | Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | CDC7 | Cell division cycle 7. (576 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) |
| | CDKN2C | Cyclin dependent kinase inhibitor 2C. (168 aa) |
| | PSMB2 | Proteasome subunit beta. (201 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) |
| | RPA2 | Replication protein A2. (270 aa) |
| | E2F2 | E2F transcription factor 2. (437 aa) |
| | CREBZF | CREB/ATF bZIP transcription factor. (354 aa) |
| | CDK1 | Protein kinase domain-containing protein. (297 aa) |
| | ENSCSAP00000017575 | Ubiquitin-like domain-containing protein. (156 aa) |
| | TFDP3 | Transcription factor. (405 aa) |
| | ENSCSAP00000017704 | E2F_TDP domain-containing protein. (281 aa) |
| | ENSCSAP00000017750 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa) |
| | ENSCSAP00000017765 | Ubiquitin-like domain-containing protein. (155 aa) |
| | ENSCSAP00000018444 | Ubiquitin-like domain-containing protein. (127 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | ENSCSAP00000019055 | Transcription factor. (409 aa) |
