STRINGSTRING
ADCY2 ADCY2 UBC UBC PSMB4 PSMB4 PSMA5 PSMA5 PRKACB PRKACB PSMD5 PSMD5 ARRB2 ARRB2 PSMB6 PSMB6 PDIA2 PDIA2 THAP7 THAP7 DERL2 DERL2 NUMB NUMB DELE1 DELE1 ITCH ITCH PSMD6 PSMD6 PDCD2 PDCD2 PSMB1 PSMB1 CSNK1A1 CSNK1A1 PSMC2 PSMC2 SEL1L2 SEL1L2 ARR3 ARR3 SEL1L SEL1L IFT140 IFT140 PRKAR2B PRKAR2B TEX52 TEX52 TULP3 TULP3 ENSCSAP00000007420 ENSCSAP00000007420 PSMD13 PSMD13 GPR161 GPR161 ADCY10 ADCY10 DZIP1L DZIP1L PSMF1 PSMF1 SPATA5L1 SPATA5L1 VCP VCP ADCY8 ADCY8 CNBD2 CNBD2 IFT172 IFT172 TULP1 TULP1 SMO SMO ADCY9 ADCY9 PSMB9 PSMB9 PSMB8 PSMB8 ENSCSAP00000005494 ENSCSAP00000005494 IFT122 IFT122 PSMD10 PSMD10 ADCY3 ADCY3 PTRHD1 PTRHD1 GRK2 GRK2 IHH IHH TUBA4A TUBA4A WDR35 WDR35 FOPNL FOPNL CUL3 CUL3 SYVN1 SYVN1 ADCY5 ADCY5 DISP2 DISP2 TUBB2A TUBB2A ADAM17 ADAM17 GSK3B GSK3B CUL1 CUL1 PSMD1 PSMD1 BOC BOC SHH SHH PTCH1 PTCH1 PSMD11 PSMD11 PRKACA PRKACA IFT57 IFT57 ADCY6 ADCY6 DHH DHH TUBA1B TUBA1B TUBA1C TUBA1C TUBA1A TUBA1A RBX1 RBX1 PSMC3 PSMC3 MKS1 MKS1 BTRC BTRC SUFU SUFU ADCY7 ADCY7 KXD1 KXD1 UBA52 UBA52 RPGRIP1L RPGRIP1L GLI1 GLI1 PSMA1 PSMA1 THAP6 THAP6 OS9 OS9 PDCD2L PDCD2L SCUBE2 SCUBE2 TUB TUB PRKAR1A PRKAR1A PSMD7 PSMD7 PSMD12 PSMD12 PSMD8 PSMD8 ARRB1 ARRB1 PSMC5 PSMC5 PSMC4 PSMC4 NUMBL NUMBL SPATA5 SPATA5 SMURF2 SMURF2 EFCAB7 EFCAB7 GLIS1 GLIS1 PSMB2 PSMB2 DISP3 DISP3 CREBZF CREBZF ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 PRKACG PRKACG GAS1 GAS1 CSNK1A1L CSNK1A1L ENSCSAP00000018444 ENSCSAP00000018444 ENSCSAP00000018510 ENSCSAP00000018510 PSMC1 PSMC1 PSMB11 PSMB11 CDC73 CDC73 PSMB7 PSMB7 SKP1 SKP1 PSMD2 PSMD2 KIF3A KIF3A ERLEC1 ERLEC1 PSME4 PSME4 IFT52 IFT52 PSMB10 PSMB10 RPS27A RPS27A ENSCSAP00000010298 ENSCSAP00000010298 ULK3 ULK3 PSMA3 PSMA3 TTC21A TTC21A PSMA4 PSMA4 PSMC6 PSMC6 OFD1 OFD1 HHAT HHAT GLI3 GLI3 PRKAR2A PRKAR2A PSMA2 PSMA2 TTC21B TTC21B PSMA6 PSMA6 GNAS GNAS TUBB1 TUBB1 PSMD14 PSMD14 PSMA7 PSMA7 ADCY1 ADCY1 ADCY4 ADCY4 ENSCSAP00000012056 ENSCSAP00000012056 ENSCSAP00000012074 ENSCSAP00000012074 DISP1 DISP1 PSME2 PSME2 PSMB5 PSMB5 EVC EVC PSME1 PSME1 EVC2 EVC2 SPOPL SPOPL TUBB4B TUBB4B GLI2 GLI2 SEL1L3 SEL1L3 CCDC13 CCDC13 HHATL HHATL WDR19 WDR19 TUBB6 TUBB6 ENSCSAP00000013550 ENSCSAP00000013550 DZIP1 DZIP1 PRKAR1B PRKAR1B IQCE IQCE SMURF1 SMURF1 PSMA8 PSMA8 IFT88 IFT88 ENSCSAP00000014414 ENSCSAP00000014414 INTU INTU HHIP HHIP PSME3 PSME3 DYNC2H1 DYNC2H1 LRP2BP LRP2BP TULP2 TULP2 PSMD3 PSMD3 ENSCSAP00000015339 ENSCSAP00000015339 GAS8 GAS8 PSMB3 PSMB3 FUZ FUZ CDON CDON P4HB P4HB NOTUM NOTUM PSMD9 PSMD9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
UBCUncharacterized protein. (228 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
ARRB2Arrestin beta 2. (409 aa)
PSMB6Proteasome subunit beta. (239 aa)
PDIA2Protein disulfide isomerase family A member 2. (524 aa)
THAP7THAP domain containing 7. (309 aa)
DERL2Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (265 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
DELE1DAP3 binding cell death enhancer 1. (522 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PDCD2Programmed cell death 2. (343 aa)
PSMB1Proteasome subunit beta. (241 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (353 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
SEL1L2SEL1L2 adaptor subunit of ERAD E3 ligase. (689 aa)
ARR3Arrestin 3. (401 aa)
SEL1LSEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
IFT140Intraflagellar transport 140. (1462 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (421 aa)
TEX52Testis expressed 52. (305 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (442 aa)
ENSCSAP00000007420Uncharacterized protein. (914 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
GPR161G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (529 aa)
ADCY10Adenylate cyclase 10. (1616 aa)
DZIP1LDAZ interacting zinc finger protein 1 like. (766 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (753 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (585 aa)
IFT172Intraflagellar transport 172. (1229 aa)
TULP1Tubby-like protein; Belongs to the TUB family. (542 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (308 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
IFT122Intraflagellar transport 122. (1241 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (448 aa)
WDR35WD repeat-containing protein 35; As a component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs), it is involved in ciliogenesis and ciliary protein trafficking. (1181 aa)
FOPNLFGFR1OP N-terminal like. (174 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
SYVN1Synoviolin 1. (617 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
DISP2Dispatched RND transporter family member 2. (1401 aa)
TUBB2ATubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
PTCH1Patched 1. (1452 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (354 aa)
IFT57Intraflagellar transport 57. (429 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
DHHDesert hedgehog signaling molecule. (298 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
TUBA1CTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
TUBA1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
RBX1Ring-box 1. (108 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
RPGRIP1LRPGRIP1 like. (1263 aa)
GLI1GLI family zinc finger 1. (1106 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
THAP6THAP domain containing 6. (222 aa)
OS9OS9 endoplasmic reticulum lectin. (668 aa)
PDCD2LPDCD2_C domain-containing protein. (332 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (944 aa)
TUBTubby-like protein; Belongs to the TUB family. (512 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
ARRB1Arrestin beta 1. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
NUMBLNUMB like endocytic adaptor protein. (602 aa)
SPATA5Uncharacterized protein. (789 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (474 aa)
EFCAB7EF-hand calcium binding domain 7. (629 aa)
GLIS1GLIS family zinc finger 1. (709 aa)
PSMB2Proteasome subunit beta. (201 aa)
DISP3Dispatched RND transporter family member 3. (1392 aa)
CREBZFCREB/ATF bZIP transcription factor. (354 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
GAS1Growth arrest specific 1. (347 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
ENSCSAP00000018510LisH domain-containing protein. (1013 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMB11Proteasome subunit beta. (300 aa)
CDC73Cell division cycle 73. (531 aa)
PSMB7Proteasome subunit beta. (277 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
KIF3AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (726 aa)
ERLEC1Endoplasmic reticulum lectin 1. (483 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
IFT52Intraflagellar transport 52. (442 aa)
PSMB10Proteasome subunit beta. (273 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000010298Uncharacterized protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (385 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
TTC21ATetratricopeptide repeat domain 21A. (1321 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
OFD1OFD1 centriole and centriolar satellite protein. (1015 aa)
HHATHedgehog acyltransferase; Belongs to the membrane-bound acyltransferase family. (514 aa)
GLI3GLI family zinc finger 3. (1459 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (404 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
GNASUncharacterized protein. (335 aa)
TUBB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
ENSCSAP00000012056Tubulin domain-containing protein; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (417 aa)
ENSCSAP00000012074Uncharacterized protein. (188 aa)
DISP1SSD domain-containing protein. (1329 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMB5Proteasome subunit beta. (263 aa)
EVCEvC ciliary complex subunit 1. (948 aa)
PSME1Proteasome activator subunit 1. (238 aa)
EVC2EvC ciliary complex subunit 2. (1311 aa)
SPOPLSpeckle type BTB/POZ protein like. (288 aa)
TUBB4BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
GLI2GLI family zinc finger 2. (1554 aa)
SEL1L3SEL1L family member 3. (1104 aa)
CCDC13Uncharacterized protein. (711 aa)
HHATLHedgehog acyltransferase like; Belongs to the membrane-bound acyltransferase family. (504 aa)
WDR19WD repeat domain 19. (1342 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (446 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
DZIP1DAZ interacting zinc finger protein 1. (825 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
IQCEIQ motif containing E. (721 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
IFT88Intraflagellar transport 88. (792 aa)
ENSCSAP00000014414AAA_lid_3 domain-containing protein. (111 aa)
INTUInturned planar cell polarity protein. (921 aa)
HHIPHedgehog interacting protein. (682 aa)
PSME3Proteasome activator subunit 3. (267 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4311 aa)
LRP2BPLRP2 binding protein. (348 aa)
TULP2TUB like protein 2; Belongs to the TUB family. (510 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
ENSCSAP00000015339Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
GAS8Growth arrest specific 8. (395 aa)
PSMB3Proteasome subunit beta. (205 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
P4HBProtein disulfide-isomerase. (510 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (354 aa)
PSMD9PDZ domain-containing protein. (223 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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