STRINGSTRING
CARD9 CARD9 PSME2 PSME2 PSMB5 PSMB5 PSME1 PSME1 IL1B IL1B TAB2 TAB2 MAP3K7 MAP3K7 ENSCSAP00000013550 ENSCSAP00000013550 CARD11 CARD11 PSMA8 PSMA8 MALT1 MALT1 NFATC1 NFATC1 PDPK1 PDPK1 PLCG2 PLCG2 PSME3 PSME3 RELB RELB PSMD3 PSMD3 PSMB3 PSMB3 PSMD9 PSMD9 UBC UBC PSMB4 PSMB4 UBE2M UBE2M AHCYL1 AHCYL1 PSMA5 PSMA5 BCL10 BCL10 PSMB2 PSMB2 ENSCSAP00000017575 ENSCSAP00000017575 UBE2NL UBE2NL ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000018444 ENSCSAP00000018444 PSMC1 PSMC1 CCDC71L CCDC71L PSMB11 PSMB11 MAP3K14 MAP3K14 ENSCSAP00000000080 ENSCSAP00000000080 PSMC4 PSMC4 PSMC5 PSMC5 PSMB10 PSMB10 NFKB1 NFKB1 NFATC3 NFATC3 ENSCSAP00000000421 ENSCSAP00000000421 PSMD8 PSMD8 PPP3CA PPP3CA NFAT5 NFAT5 PSMD12 PSMD12 PSMD7 PSMD7 PSMA1 PSMA1 UBA52 UBA52 KXD1 KXD1 NFKB2 NFKB2 TRAF6 TRAF6 BTRC BTRC CHUK CHUK PYCARD PYCARD PSMC3 PSMC3 TAB1 TAB1 PSMD11 PSMD11 IKBKG IKBKG PSMD1 PSMD1 CUL1 CUL1 SYK SYK UBE2D1 UBE2D1 ITPR2 ITPR2 RELA RELA PPP3CB PPP3CB PSMD10 PSMD10 CLEC7A CLEC7A ENSCSAP00000005494 ENSCSAP00000005494 PSMB8 PSMB8 PSMB9 PSMB9 FBXW11 FBXW11 ITPR3 ITPR3 PSMF1 PSMF1 CASP8 CASP8 ITPR1 ITPR1 PSMD13 PSMD13 UBA3 UBA3 PSMC2 PSMC2 PSMB1 PSMB1 PSMD6 PSMD6 PSMB6 PSMB6 CDC34 CDC34 PRKCD PRKCD PSMD5 PSMD5 PSMB7 PSMB7 SKP1 SKP1 PSMD2 PSMD2 SRC SRC PSME4 PSME4 RPS27A RPS27A TAB3 TAB3 PSMA3 PSMA3 MAP3K20 MAP3K20 ENSCSAP00000010823 ENSCSAP00000010823 WDR92 WDR92 PPP3R1 PPP3R1 PSMA4 PSMA4 PSMC6 PSMC6 IKBKB IKBKB TMEM189-UBE2V1 TMEM189-UBE2V1 NFATC2 NFATC2 PSMA2 PSMA2 NFKBIA NFKBIA PSMA6 PSMA6 PSMD14 PSMD14 PSMA7 PSMA7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CARD9Caspase recruitment domain family member 9. (499 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator subunit 1. (238 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
CARD11Caspase recruitment domain family member 11. (805 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
MALT1MALT1 paracaspase. (729 aa)
NFATC1Nuclear factor of activated T cells 1. (929 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (580 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
PSME3Proteasome activator subunit 3. (267 aa)
RELBRELB proto-oncogene, NF-kB subunit. (440 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD9PDZ domain-containing protein. (223 aa)
UBCUncharacterized protein. (228 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
UBE2MUbiquitin conjugating enzyme E2 M; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
BCL10BCL10 immune signaling adaptor. (233 aa)
PSMB2Proteasome subunit beta. (201 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
PSMB11Proteasome subunit beta. (300 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
ENSCSAP00000000080UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (199 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
NFATC3RHD domain-containing protein. (637 aa)
ENSCSAP00000000421Uncharacterized protein. (398 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
NFAT5Nuclear factor of activated T cells 5. (1548 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (176 aa)
NFKB2Nuclear factor kappa B subunit 2. (899 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (338 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
SYKTyrosine-protein kinase. (635 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
CLEC7AC-type lectin domain containing 7A. (259 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMB8Proteasome subunit beta. (308 aa)
PSMB9Proteasome subunit beta. (219 aa)
FBXW11F-box and WD repeat domain containing 11. (510 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (496 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (463 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PSMB6Proteasome subunit beta. (239 aa)
CDC34Cell division cycle 34; Belongs to the ubiquitin-conjugating enzyme family. (236 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB7Proteasome subunit beta. (277 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SRCTyrosine-protein kinase. (633 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
MAP3K20Protein kinase domain-containing protein. (292 aa)
ENSCSAP00000010823Protein kinase domain-containing protein. (169 aa)
WDR92WD repeat domain 92. (357 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
TMEM189-UBE2V1TMEM189-UBE2V1 readthrough. (370 aa)
NFATC2Nuclear factor of activated T cells 2. (928 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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