STRINGSTRING
PSMD1 PSMD1 PSMC4 PSMC4 PSMC5 PSMC5 PSMB10 PSMB10 PSMD8 PSMD8 CUL1 CUL1 PSMD12 PSMD12 PSMD7 PSMD7 PSMA1 PSMA1 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017575 ENSCSAP00000017575 PSMB2 PSMB2 PRKACB PRKACB PSMA5 PSMA5 PSMB4 PSMB4 UBC UBC PSMD9 PSMD9 PSMB3 PSMB3 PSMD3 PSMD3 PSME3 PSME3 PSMA8 PSMA8 ENSCSAP00000013550 ENSCSAP00000013550 CSNK1A1L CSNK1A1L ENSCSAP00000018444 ENSCSAP00000018444 PSMC1 PSMC1 PSMB11 PSMB11 PSME1 PSME1 PSMB5 PSMB5 PSME2 PSME2 PSMA7 PSMA7 PSMD14 PSMD14 PSMA6 PSMA6 PSMA2 PSMA2 GLI3 GLI3 PSMC6 PSMC6 PSMA4 PSMA4 PSMA3 PSMA3 RPS27A RPS27A PSME4 PSME4 PSMD2 PSMD2 SKP1 SKP1 PSMB7 PSMB7 PSMD5 PSMD5 PSMB6 PSMB6 PSMD6 PSMD6 PSMB1 PSMB1 CSNK1A1 CSNK1A1 PSMC2 PSMC2 PSMD13 PSMD13 PRKACG PRKACG PSMF1 PSMF1 PSMB9 PSMB9 PSMB8 PSMB8 ENSCSAP00000005494 ENSCSAP00000005494 PSMD10 PSMD10 GSK3B GSK3B UBA52 UBA52 SUFU SUFU BTRC BTRC PSMC3 PSMC3 RBX1 RBX1 PRKACA PRKACA PSMD11 PSMD11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
PSMB2Proteasome subunit beta. (201 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
UBCUncharacterized protein. (228 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSME3Proteasome activator subunit 3. (267 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (337 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
PSMB11Proteasome subunit beta. (300 aa)
PSME1Proteasome activator subunit 1. (238 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
GLI3GLI family zinc finger 3. (1459 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PSMB1Proteasome subunit beta. (241 aa)
CSNK1A1Casein kinase 1 alpha 1; Belongs to the protein kinase superfamily. (353 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (308 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
RBX1Ring-box 1. (108 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (354 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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