node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSDE1 | FGF18 | ENSCSAP00000016368 | ENSCSAP00000005916 | Cold shock domain containing E1. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.440 |
CSDE1 | GRB2 | ENSCSAP00000016368 | ENSCSAP00000001067 | Cold shock domain containing E1. | Growth factor receptor bound protein 2. | 0.602 |
CSDE1 | PIK3CA | ENSCSAP00000016368 | ENSCSAP00000009123 | Cold shock domain containing E1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.653 |
CSDE1 | PTPN11 | ENSCSAP00000016368 | ENSCSAP00000015571 | Cold shock domain containing E1. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.480 |
CSDE1 | SOS1 | ENSCSAP00000016368 | ENSCSAP00000008547 | Cold shock domain containing E1. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.629 |
ERAS | FGF18 | ENSCSAP00000019063 | ENSCSAP00000005916 | ES cell expressed Ras. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.440 |
ERAS | FGF4 | ENSCSAP00000019063 | ENSCSAP00000005550 | ES cell expressed Ras. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.519 |
ERAS | GRB2 | ENSCSAP00000019063 | ENSCSAP00000001067 | ES cell expressed Ras. | Growth factor receptor bound protein 2. | 0.602 |
ERAS | HRAS | ENSCSAP00000019063 | ENSCSAP00000007252 | ES cell expressed Ras. | HRas proto-oncogene, GTPase. | 0.513 |
ERAS | PIK3CA | ENSCSAP00000019063 | ENSCSAP00000009123 | ES cell expressed Ras. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.710 |
ERAS | PIK3R1 | ENSCSAP00000019063 | ENSCSAP00000011965 | ES cell expressed Ras. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.502 |
ERAS | PTPN11 | ENSCSAP00000019063 | ENSCSAP00000015571 | ES cell expressed Ras. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.557 |
ERAS | SHC1 | ENSCSAP00000019063 | ENSCSAP00000016061 | ES cell expressed Ras. | SHC adaptor protein 1. | 0.440 |
ERAS | SOS1 | ENSCSAP00000019063 | ENSCSAP00000008547 | ES cell expressed Ras. | SOS Ras/Rac guanine nucleotide exchange factor 1. | 0.766 |
FGF1 | FGF17 | ENSCSAP00000008567 | ENSCSAP00000012642 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.666 |
FGF1 | FGF18 | ENSCSAP00000008567 | ENSCSAP00000005916 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.560 |
FGF1 | FGF19 | ENSCSAP00000008567 | ENSCSAP00000005540 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.525 |
FGF1 | FGF2 | ENSCSAP00000008567 | ENSCSAP00000000029 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.645 |
FGF1 | FGF23 | ENSCSAP00000008567 | ENSCSAP00000007334 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | 0.776 |
FGF1 | FGF4 | ENSCSAP00000008567 | ENSCSAP00000005550 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.577 |