STRINGSTRING
PPP2R1A PPP2R1A ENSCSAP00000019219 ENSCSAP00000019219 FGFBP1 FGFBP1 ERAS ERAS ENSCSAP00000018444 ENSCSAP00000018444 ENSCSAP00000018390 ENSCSAP00000018390 SPRY2 SPRY2 LOC103214464 LOC103214464 FGFBP3 FGFBP3 ENSCSAP00000017844 ENSCSAP00000017844 ENSCSAP00000017765 ENSCSAP00000017765 NCBP2L NCBP2L ENSCSAP00000017575 ENSCSAP00000017575 LOC103247992 LOC103247992 MKNK1 MKNK1 PTBP2 PTBP2 NRAS NRAS CSDE1 CSDE1 SHC1 SHC1 UBC UBC PTPN11 PTPN11 CBL CBL GAB1 GAB1 POLR2J POLR2J FGF9 FGF9 GTF2F2 GTF2F2 FNDC3A FNDC3A POLR2D POLR2D FGF20 FGF20 FGF10 FGF10 FGF17 FGF17 PIK3R1 PIK3R1 PPP2CB PPP2CB TIA1 TIA1 RPS27A RPS27A PLCG1 PLCG1 POLR2H POLR2H SRC SRC MAPK1 MAPK1 PPP2CA PPP2CA PIK3CA PIK3CA FGF22 FGF22 FNDC3B FNDC3B PTBP1 PTBP1 ESRP1 ESRP1 FGF1 FGF1 SOS1 SOS1 POLR2E POLR2E PTBP3 PTBP3 POLR2K POLR2K MKNK2 MKNK2 POLR2A POLR2A FRS3 FRS3 FGF23 FGF23 FGF6 FGF6 HRAS HRAS NCBP1 NCBP1 FGF16 FGF16 FGF7 FGF7 POLR2L POLR2L ENSCSAP00000006444 ENSCSAP00000006444 FGF18 FGF18 GTF2F1 GTF2F1 FGF3 FGF3 FGF4 FGF4 NCBP2 NCBP2 BRAF BRAF RBFOX2 RBFOX2 HNRNPM HNRNPM KRAS KRAS POLR2F POLR2F POLR2G POLR2G MAPK3 MAPK3 FGF8 FGF8 HNRNPA1 HNRNPA1 UBA52 UBA52 POLR2B POLR2B POLR2C POLR2C ENSCSAP00000001097 ENSCSAP00000001097 GRB2 GRB2 TIAL1 TIAL1 FGFR2 FGFR2 FGF5 FGF5 POLR2I POLR2I FRS2 FRS2 ESRP2 ESRP2 FGF2 FGF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
ENSCSAP00000019219Uncharacterized protein. (320 aa)
FGFBP1Fibroblast growth factor binding protein 1. (234 aa)
ERASES cell expressed Ras. (233 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
ENSCSAP00000018390Uncharacterized protein. (320 aa)
SPRY2Sprouty RTK signaling antagonist 2. (315 aa)
LOC103214464Uncharacterized protein. (319 aa)
FGFBP3Fibroblast growth factor binding protein 3. (260 aa)
ENSCSAP00000017844Uncharacterized protein. (372 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
LOC103247992Uncharacterized protein. (320 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (418 aa)
PTBP2Polypyrimidine tract binding protein 2. (531 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (844 aa)
SHC1SHC adaptor protein 1. (474 aa)
UBCUncharacterized protein. (228 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
CBLCbl proto-oncogene. (907 aa)
GAB1GRB2 associated binding protein 1. (751 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
GTF2F2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (249 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
FGF17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (333 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PPP2CBSerine/threonine-protein phosphatase. (309 aa)
TIA1TIA1 cytotoxic granule associated RNA binding protein. (386 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
POLR2HRNA polymerase II subunit H. (187 aa)
SRCTyrosine-protein kinase. (633 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (170 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PTBP1Polypyrimidine tract binding protein 1. (556 aa)
ESRP1Epithelial splicing regulatory protein 1. (663 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
PTBP3Polypyrimidine tract binding protein 3. (524 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (465 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1971 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
FGF23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (115 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
ENSCSAP00000006444Uncharacterized protein. (304 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (438 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (239 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (235 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (482 aa)
RBFOX2RNA binding protein fox-1 homolog 2; RNA-binding protein that regulates alternative splicing events. (366 aa)
HNRNPMHeterogeneous nuclear ribonucleoprotein M. (692 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HNRNPA1Heterogeneous nuclear ribonucleoprotein A1. (372 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
ENSCSAP00000001097Uncharacterized protein. (267 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (375 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (268 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
ESRP2Epithelial splicing regulatory protein 2. (715 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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