STRINGSTRING
DNAJB13 DNAJB13 PSMC4 PSMC4 PAK1 PAK1 PSMC5 PSMC5 PSMB10 PSMB10 PSMD8 PSMD8 PSMD12 PSMD12 PSMD7 PSMD7 PSMA1 PSMA1 UBA52 UBA52 KXD1 KXD1 RAG1 RAG1 PSMC3 PSMC3 TNRC6B TNRC6B DNAJB1 DNAJB1 PRKACA PRKACA PSMD11 PSMD11 CDC14B CDC14B PSMD1 PSMD1 KALRN KALRN PAK2 PAK2 PAK3 PAK3 PSMD10 PSMD10 ENSCSAP00000005494 ENSCSAP00000005494 PSMB8 PSMB8 PSMB9 PSMB9 AGO2 AGO2 BRSK2 BRSK2 MYC MYC DNAJB5 DNAJB5 PSMF1 PSMF1 PSMD13 PSMD13 CCND3 CCND3 MAPK6 MAPK6 PSMC2 PSMC2 PSMB1 PSMB1 PSMD6 PSMD6 PSMB6 PSMB6 PSMD5 PSMD5 ETV1 ETV1 PSMB7 PSMB7 PSMD2 PSMD2 PSME4 PSME4 RPS27A RPS27A PSMA3 PSMA3 XPO1 XPO1 CDKN3 CDKN3 NCOA3 NCOA3 PSMA4 PSMA4 SEPTIN7 SEPTIN7 PSMC6 PSMC6 TMEM232 TMEM232 FOXO3 FOXO3 PSMA2 PSMA2 PSMA6 PSMA6 PSMD14 PSMD14 PSMA7 PSMA7 RSPH4A RSPH4A PSME2 PSME2 PSMB5 PSMB5 PSME1 PSME1 ENSCSAP00000013550 ENSCSAP00000013550 PSMA8 PSMA8 FOXO1 FOXO1 MAPK4 MAPK4 HSPB1 HSPB1 ETV4 ETV4 PSME3 PSME3 RSPH6A RSPH6A PSMD3 PSMD3 PSMB3 PSMB3 MAPKAPK5 MAPKAPK5 IGF2BP1 IGF2BP1 DUSP23 DUSP23 PSMD9 PSMD9 UBC UBC PSMB4 PSMB4 BRSK1 BRSK1 MOV10 MOV10 PSMA5 PSMA5 CDC14A CDC14A PRKACB PRKACB DNAJB4 DNAJB4 AGO3 AGO3 AGO1 AGO1 AGO4 AGO4 PSMB2 PSMB2 CDC42 CDC42 CDK1 CDK1 ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 JUN JUN PRKACG PRKACG ENSCSAP00000018444 ENSCSAP00000018444 PSMC1 PSMC1 CDC42EP2 CDC42EP2 RAG2 RAG2 CDC42EP3 CDC42EP3 CDC14C CDC14C CDC42EP5 CDC42EP5 PSMB11 PSMB11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNAJB13DnaJ heat shock protein family (Hsp40) member B13. (349 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (176 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (953 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1773 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (354 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
CDC14BCell division cycle 14B. (461 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
KALRNKalirin RhoGEF kinase. (2512 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMB8Proteasome subunit beta. (308 aa)
PSMB9Proteasome subunit beta. (219 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (904 aa)
BRSK2BR serine/threonine kinase 2. (690 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
DNAJB5DnaJ heat shock protein family (Hsp40) member B5. (420 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
MAPK6Mitogen-activated protein kinase 6. (721 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
ETV1ETS variant 1. (477 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
XPO1Exportin 1. (1071 aa)
CDKN3Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. (212 aa)
NCOA3Nuclear receptor coactivator. (1417 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (384 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
TMEM232Transmembrane protein 232. (485 aa)
FOXO3Forkhead box O3. (672 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
RSPH4ARadial spoke head component 4A. (719 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator subunit 1. (238 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
FOXO1Forkhead box O1. (655 aa)
MAPK4Mitogen-activated protein kinase 4. (587 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (143 aa)
ETV4ETS variant 4. (415 aa)
PSME3Proteasome activator subunit 3. (267 aa)
RSPH6ARadial spoke head 6 homolog A. (717 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
MAPKAPK5MAPK activated protein kinase 5. (412 aa)
IGF2BP1Insulin like growth factor 2 mRNA binding protein 1. (577 aa)
DUSP23Dual specificity phosphatase 23. (150 aa)
PSMD9PDZ domain-containing protein. (223 aa)
UBCUncharacterized protein. (228 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
BRSK1BR serine/threonine kinase 1. (703 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
CDC14ACell division cycle 14A. (595 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
DNAJB4DnaJ heat shock protein family (Hsp40) member B4. (337 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
PSMB2Proteasome subunit beta. (201 aa)
CDC42Cell division cycle 42. (191 aa)
CDK1Protein kinase domain-containing protein. (297 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
CDC42EP2CDC42 effector protein 2. (216 aa)
RAG2Recombination activating 2. (527 aa)
CDC42EP3CDC42 effector protein 3. (254 aa)
CDC14CCell division cycle 14C. (484 aa)
CDC42EP5CDC42 effector protein 5. (147 aa)
PSMB11Proteasome subunit beta. (300 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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