STRINGSTRING
POLD4 POLD4 GTF2H4 GTF2H4 ERCC4 ERCC4 ENSCSAP00000003124 ENSCSAP00000003124 DDB1 DDB1 RBX1 RBX1 DDB2 DDB2 KXD1 KXD1 UBA52 UBA52 GTF2H1 GTF2H1 POLD3 POLD3 UBC UBC RPA1 RPA1 PARP3 PARP3 RPS27A RPS27A POLE2 POLE2 POLK POLK POLD2 POLD2 GTF2H2 GTF2H2 POLE4 POLE4 PARP1 PARP1 PARP2 PARP2 ERCC3 ERCC3 RFC1 RFC1 CUL4A CUL4A ERCC5 ERCC5 BIVM BIVM RCBTB1 RCBTB1 RCBTB2 RCBTB2 RFC3 RFC3 RFC2 RFC2 CUL4B CUL4B CHD1L CHD1L ERCC2 ERCC2 ERCC1 ERCC1 RFC5 RFC5 POLD1 POLD1 GTF2H3 GTF2H3 POLE POLE ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000018444 ENSCSAP00000018444 PCNA PCNA RPA3 RPA3 GTF2H5 GTF2H5 POLE3 POLE3 XPA XPA RFC4 RFC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLD4Uncharacterized protein. (107 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (735 aa)
ENSCSAP00000003124BTB domain-containing protein. (463 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
RBX1Ring-box 1. (108 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLD3Uncharacterized protein. (466 aa)
UBCUncharacterized protein. (228 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
PARP3Poly [ADP-ribose] polymerase. (532 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
POLKDNA polymerase kappa. (847 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (117 aa)
PARP1Poly(ADP-ribose) polymerase 1. (709 aa)
PARP2Poly(ADP-ribose) polymerase 2. (570 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
RFC1Replication factor C subunit 1. (985 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
ERCC5ERCC excision repair 5, endonuclease. (1182 aa)
BIVMBasic, immunoglobulin-like variable motif containing. (503 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
RFC3Replication factor C subunit 3. (356 aa)
RFC2Replication factor C subunit 2. (353 aa)
CUL4BCullin 4B; Belongs to the cullin family. (900 aa)
CHD1LChromodomain helicase DNA binding protein 1 like. (900 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (736 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
RFC5Replication factor C subunit 5. (340 aa)
POLD1DNA polymerase. (1086 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RPA3Replication protein A3. (121 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
XPAXPA, DNA damage recognition and repair factor. (226 aa)
RFC4Replication factor C subunit 4. (363 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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