STRINGSTRING
RPS27A RPS27A AQR AQR ERCC4 ERCC4 GTF2H4 GTF2H4 XAB2 XAB2 HMGN1 HMGN1 POLD4 POLD4 USP7 USP7 ISY1 ISY1 RFC4 RFC4 ERCC6 ERCC6 POLR2L POLR2L XPA XPA MEIOB MEIOB NRDE2 NRDE2 POLR2A POLR2A ENSCSAP00000007810 ENSCSAP00000007810 POLR2K POLR2K POLR2E POLR2E POLE3 POLE3 GTF2H5 GTF2H5 RPA3 RPA3 PCNA PCNA PHF3 PHF3 POLR2H POLR2H RPA1 RPA1 MNAT1 MNAT1 TCEA1 TCEA1 CCNH CCNH POLE2 POLE2 POLK POLK POLD2 POLD2 UVSSA UVSSA GTF2H2 GTF2H2 POLE4 POLE4 CDK7 CDK7 ERCC8 ERCC8 TCEA2 TCEA2 ERCC3 ERCC3 POLR2D POLR2D RFC1 RFC1 ENSCSAP00000013457 ENSCSAP00000013457 CUL4A CUL4A ERCC5 ERCC5 BIVM BIVM RCBTB1 RCBTB1 RCBTB2 RCBTB2 RFC3 RFC3 POLR2J POLR2J LOC103246669 LOC103246669 RFC2 RFC2 CUL4B CUL4B ERCC2 ERCC2 ERCC1 ERCC1 RFC5 RFC5 POLD1 POLD1 GTF2H3 GTF2H3 UBC UBC POLE POLE TCEANC2 TCEANC2 PPIE PPIE SPOCD1 SPOCD1 TCEA3 TCEA3 ZNF830 ZNF830 ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000018423 ENSCSAP00000018423 ENSCSAP00000018444 ENSCSAP00000018444 ENSCSAP00000018526 ENSCSAP00000018526 TCEANC TCEANC HMGN2 HMGN2 POLR2I POLR2I POLD3 POLD3 POLR2F POLR2F ENSCSAP00000003124 ENSCSAP00000003124 POLR2G POLR2G ATAD5 ATAD5 DDB1 DDB1 USP40 USP40 PRPF19 PRPF19 RBX1 RBX1 EP300 EP300 KXD1 KXD1 UBA52 UBA52 POLR2B POLR2B GTF2H1 GTF2H1 POLR2C POLR2C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS27AUbiquitin-like domain-containing protein. (156 aa)
AQRRNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (735 aa)
GTF2H4General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (462 aa)
XAB2XPA binding protein 2. (855 aa)
HMGN1High mobility group nucleosome binding domain 1. (158 aa)
POLD4Uncharacterized protein. (107 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1102 aa)
ISY1Uncharacterized protein. (285 aa)
RFC4Replication factor C subunit 4. (363 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1494 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
XPAXPA, DNA damage recognition and repair factor. (226 aa)
MEIOBMeiosis specific with OB-fold. (472 aa)
NRDE2NRDE-2, necessary for RNA interference, domain containing. (1164 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1971 aa)
ENSCSAP00000007810Uncharacterized protein. (88 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
POLR2ERNA polymerase II subunit E. (210 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
RPA3Replication protein A3. (121 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
PHF3PHD finger protein 3. (2039 aa)
POLR2HRNA polymerase II subunit H. (187 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
TCEA1Transcription elongation factor A1. (301 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
POLKDNA polymerase kappa. (847 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
UVSSAUV stimulated scaffold protein A. (709 aa)
GTF2H2General transcription factor IIH subunit. (395 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (117 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
TCEA2Transcription elongation factor A2. (299 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa)
POLR2DRNA polymerase II subunit D. (142 aa)
RFC1Replication factor C subunit 1. (985 aa)
ENSCSAP00000013457Uncharacterized protein. (92 aa)
CUL4ACullin 4A; Belongs to the cullin family. (759 aa)
ERCC5ERCC excision repair 5, endonuclease. (1182 aa)
BIVMBasic, immunoglobulin-like variable motif containing. (503 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (531 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (551 aa)
RFC3Replication factor C subunit 3. (356 aa)
POLR2JRNA polymerase II subunit J. (117 aa)
LOC103246669Uncharacterized protein. (266 aa)
RFC2Replication factor C subunit 2. (353 aa)
CUL4BCullin 4B; Belongs to the cullin family. (900 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (736 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
RFC5Replication factor C subunit 5. (340 aa)
POLD1DNA polymerase. (1086 aa)
GTF2H3General transcription factor IIH subunit 3. (309 aa)
UBCUncharacterized protein. (228 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2288 aa)
TCEANC2Transcription elongation factor A N-terminal and central domain containing 2. (208 aa)
PPIEPeptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (304 aa)
SPOCD1SPOC domain containing 1. (1212 aa)
TCEA3Transcription elongation factor A3. (248 aa)
ZNF830Zinc finger protein 830. (372 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000018423Uncharacterized protein. (88 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
ENSCSAP00000018526Uncharacterized protein. (90 aa)
TCEANCTranscription elongation factor A N-terminal and central domain containing. (350 aa)
HMGN2Uncharacterized protein. (90 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLD3Uncharacterized protein. (466 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
ENSCSAP00000003124BTB domain-containing protein. (463 aa)
POLR2GRNA polymerase II subunit G. (172 aa)
ATAD5ATPase family AAA domain containing 5. (1838 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
USP40Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family. (1236 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
RBX1Ring-box 1. (108 aa)
EP300E1A binding protein p300. (2416 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1167 aa)
GTF2H1General transcription factor IIH subunit 1. (548 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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