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BCO2 BCO2 LRP3 LRP3 LRP1 LRP1 VKORC1 VKORC1 PYROXD2 PYROXD2 GPC1 GPC1 RBP4 RBP4 LDLR LDLR ENSCSAP00000004032 ENSCSAP00000004032 GPC3 GPC3 GPC4 GPC4 SDC1 SDC1 APOB APOB ENSCSAP00000004609 ENSCSAP00000004609 GPIHBP1 GPIHBP1 CLPS CLPS PLB1 PLB1 RBP2 RBP2 RBP1 RBP1 LRP12 LRP12 SDC2 SDC2 RDH11 RDH11 ENSCSAP00000009878 ENSCSAP00000009878 ENSCSAP00000009915 ENSCSAP00000009915 AKR1C8P AKR1C8P ENSCSAP00000010016 ENSCSAP00000010016 AKR1C3 AKR1C3 TTPAL TTPAL TTPA TTPA SDC4 SDC4 LRP2 LRP2 RETSAT RETSAT LRP1B LRP1B LRP10 LRP10 LPL LPL TTR TTR GPC2 GPC2 VKORC1L1 VKORC1L1 BCO1 BCO1 LRAT LRAT APOE APOE APOC2 APOC2 APOA4 APOA4 APOC3 APOC3 APOA1 APOA1 APOA2 APOA2 LRP8 LRP8 SDC3 SDC3 HSPG2 HSPG2 UBIAD1 UBIAD1 AGRN AGRN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BCO2Beta-carotene oxygenase 2. (579 aa)
LRP3LDL receptor related protein 3. (770 aa)
LRP1LDL receptor related protein 1. (4544 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (163 aa)
PYROXD2Pyridine nucleotide-disulphide oxidoreductase domain 2. (581 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
LDLRLow density lipoprotein receptor. (767 aa)
ENSCSAP00000004032Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (119 aa)
GPC3Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (452 aa)
GPC4Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
APOBApolipoprotein B. (4555 aa)
ENSCSAP00000004609Uncharacterized protein. (553 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (210 aa)
CLPSColipase. (128 aa)
PLB1Phospholipase B1. (1464 aa)
RBP2Retinol binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
RBP1Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
LRP12LDL receptor related protein 12. (859 aa)
SDC2Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (202 aa)
RDH11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
ENSCSAP00000009878Aldo_ket_red domain-containing protein. (324 aa)
ENSCSAP00000009915Aldo_ket_red domain-containing protein. (285 aa)
AKR1C8PAldo-keto reductase family 1 member C8, pseudogene. (323 aa)
ENSCSAP00000010016Aldo_ket_red domain-containing protein. (323 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (326 aa)
TTPALAlpha tocopherol transfer protein like. (342 aa)
TTPAAlpha tocopherol transfer protein. (239 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
LRP2LDL receptor related protein 2. (3861 aa)
RETSATRetinol saturase. (610 aa)
LRP1BLDL receptor related protein 1B. (4417 aa)
LRP10LDL receptor related protein 10. (716 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa)
GPC2Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa)
VKORC1L1Vitamin K epoxide reductase complex subunit 1 like 1. (176 aa)
BCO1Beta-carotene oxygenase 1. (546 aa)
LRATLecithin retinol acyltransferase. (230 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
APOC2Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa)
APOA4Apolipoprotein A4. (429 aa)
APOC3Apolipoprotein C3. (99 aa)
APOA1Apolipoprotein A1. (267 aa)
APOA2Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. (100 aa)
LRP8LDL receptor related protein 8. (1002 aa)
SDC3Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (346 aa)
HSPG2Heparan sulfate proteoglycan 2. (4391 aa)
UBIAD1UbiA prenyltransferase domain containing 1. (338 aa)
AGRNAgrin. (2067 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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