STRINGSTRING
PSMA4 PSMA4 PSMB11 PSMB11 PSMC1 PSMC1 ENSCSAP00000018444 ENSCSAP00000018444 UBE2C UBE2C ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017576 ENSCSAP00000017576 ENSCSAP00000017575 ENSCSAP00000017575 PSMB2 PSMB2 ORC1 ORC1 PSMA5 PSMA5 UBE2S UBE2S PSMB4 PSMB4 UBC UBC PSMD9 PSMD9 ANAPC5 ANAPC5 ANAPC11 ANAPC11 PSMB3 PSMB3 ANAPC7 ANAPC7 PSMD3 PSMD3 CDC6 CDC6 CDT1 CDT1 PSME3 PSME3 ANAPC10 ANAPC10 CCNA1 CCNA1 MCM7 MCM7 PSMA8 PSMA8 ENSCSAP00000013550 ENSCSAP00000013550 CDC16 CDC16 ORC3 ORC3 SKP2 SKP2 ANAPC1 ANAPC1 ANAPC4 ANAPC4 ANAPC2 ANAPC2 MCM6 MCM6 ORC4 ORC4 PSME1 PSME1 PSMB5 PSMB5 PSME2 PSME2 MCM9 MCM9 PSMA7 PSMA7 PSMD14 PSMD14 PSMA6 PSMA6 PSMA2 PSMA2 PSMC6 PSMC6 MCM4 MCM4 ENSCSAP00000010629 ENSCSAP00000010629 PSMA3 PSMA3 RPS27A RPS27A PSME4 PSME4 PSMD2 PSMD2 SKP1 SKP1 PSMB7 PSMB7 MCM8 MCM8 CDC23 CDC23 PSMD5 PSMD5 MCM3 MCM3 PSMB6 PSMB6 CCNE2 CCNE2 CDC26 CDC26 PSMD6 PSMD6 PSMB1 PSMB1 PSMC2 PSMC2 ORC5 ORC5 PSMD13 PSMD13 FZR1 FZR1 ORC2 ORC2 PSMF1 PSMF1 FAM89A FAM89A UBE2E1 UBE2E1 PSMB9 PSMB9 PSMB8 PSMB8 ENSCSAP00000005494 ENSCSAP00000005494 PSMD10 PSMD10 TM4SF19 TM4SF19 ANAPC16 ANAPC16 MCM2 MCM2 MCM5 MCM5 FAM89B FAM89B GMNN GMNN TM7SF3 TM7SF3 UBE2D1 UBE2D1 CUL1 CUL1 PSMD1 PSMD1 PSMD11 PSMD11 RBX1 RBX1 PSMC3 PSMC3 ORC6 ORC6 KXD1 KXD1 UBA52 UBA52 CDK2 CDK2 CDK3 CDK3 CCNE1 CCNE1 PSMA1 PSMA1 ANAPC15 ANAPC15 PSMD7 PSMD7 PSMD12 PSMD12 PSMD8 PSMD8 PSMB10 PSMB10 PSMC5 PSMC5 CDC27 CDC27 PSMC4 PSMC4 CCNA2 CCNA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMA4Proteasome subunit alpha type. (261 aa)
PSMB11Proteasome subunit beta. (300 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
UBE2CUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017576UBIQUITIN_CONJUGAT_2 domain-containing protein. (175 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
PSMB2Proteasome subunit beta. (201 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
UBE2SUbiquitin conjugating enzyme E2 S; Belongs to the ubiquitin-conjugating enzyme family. (222 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
UBCUncharacterized protein. (228 aa)
PSMD9PDZ domain-containing protein. (223 aa)
ANAPC5Anaphase promoting complex subunit 5. (742 aa)
ANAPC11RING-type domain-containing protein. (84 aa)
PSMB3Proteasome subunit beta. (205 aa)
ANAPC7Anaphase promoting complex subunit 7. (346 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
CDT1Chromatin licensing and DNA replication factor 1. (551 aa)
PSME3Proteasome activator subunit 3. (267 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (719 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
CDC16Cell division cycle 16. (620 aa)
ORC3Origin recognition complex subunit 3. (711 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
ANAPC1Anaphase promoting complex subunit 1. (1944 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (786 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
PSME1Proteasome activator subunit 1. (238 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME2Proteasome activator subunit 2. (253 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
ENSCSAP00000010629UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (181 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMB7Proteasome subunit beta. (277 aa)
MCM8MCM domain-containing protein; Belongs to the MCM family. (840 aa)
CDC23Cell division cycle 23. (597 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
MCM3DNA helicase; Belongs to the MCM family. (808 aa)
PSMB6Proteasome subunit beta. (239 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (383 aa)
CDC26Cell division cycle 26. (85 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
FZR1Fizzy and cell division cycle 20 related 1. (493 aa)
ORC2Origin recognition complex subunit 2. (577 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
FAM89AFamily with sequence similarity 89 member A. (184 aa)
UBE2E1Ubiquitin conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (308 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
TM4SF19Uncharacterized protein. (209 aa)
ANAPC16Anaphase promoting complex subunit 16. (110 aa)
MCM2DNA helicase; Belongs to the MCM family. (738 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
FAM89BFamily with sequence similarity 89 member B. (189 aa)
GMNNGeminin DNA replication inhibitor. (209 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
RBX1Ring-box 1. (108 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (314 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (416 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
ANAPC15Uncharacterized protein. (121 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
CDC27Cell division cycle 27. (824 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.