STRINGSTRING
CCNA2 CCNA2 AKT2 AKT2 PSMC4 PSMC4 E2F4 E2F4 PSMC5 PSMC5 PSMB10 PSMB10 PSMD8 PSMD8 PSMD12 PSMD12 PSMD7 PSMD7 LIN37 LIN37 LIN54 LIN54 WEE1 WEE1 CDK4 CDK4 PSMA1 PSMA1 CCNE1 CCNE1 CDK3 CDK3 CDK2 CDK2 RBL2 RBL2 UBA52 UBA52 KXD1 KXD1 PSMC3 PSMC3 PSMD11 PSMD11 PSMD1 PSMD1 CUL1 CUL1 CKS2 CKS2 WEE2 WEE2 CDKN1B CDKN1B PSMD10 PSMD10 ENSCSAP00000005494 ENSCSAP00000005494 CCND1 CCND1 AKT3 AKT3 PSMB8 PSMB8 PSMB9 PSMB9 AKT1 AKT1 MYC MYC CDKN1A CDKN1A ENSCSAP00000006740 ENSCSAP00000006740 ENSCSAP00000006748 ENSCSAP00000006748 PSMF1 PSMF1 PSMD13 PSMD13 PSMC2 PSMC2 PSMB1 PSMB1 PSMD6 PSMD6 E2F1 E2F1 CCNE2 CCNE2 LIN52 LIN52 PSMB6 PSMB6 E2F5 E2F5 PSMD5 PSMD5 MAX MAX PSMB7 PSMB7 SKP1 SKP1 PSMD2 PSMD2 RPS27A RPS27A MNAT1 MNAT1 PSMA3 PSMA3 CCNH CCNH PSMA4 PSMA4 PSMC6 PSMC6 PSMA2 PSMA2 PSMA6 PSMA6 PSMD14 PSMD14 PSMA7 PSMA7 CDK7 CDK7 CDC25A CDC25A PSME2 PSME2 PSMB5 PSMB5 PSME1 PSME1 LIN9 LIN9 PTK6 PTK6 SKP2 SKP2 TFDP1 TFDP1 ENSCSAP00000013550 ENSCSAP00000013550 CABLES1 CABLES1 RB1 RB1 CCNA1 CCNA1 PSME3 PSME3 PSMD3 PSMD3 PSMB3 PSMB3 PSMD9 PSMD9 UBC UBC PSMB4 PSMB4 PSMA5 PSMA5 PSMB2 PSMB2 CREBZF CREBZF ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000018444 ENSCSAP00000018444 PSMC1 PSMC1 ENSCSAP00000019055 ENSCSAP00000019055
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
AKT2Non-specific serine/threonine protein kinase. (535 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
E2F4E2F transcription factor 4. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
LIN37Lin-37 DREAM MuvB core complex component. (246 aa)
LIN54Lin-54 DREAM MuvB core complex component. (749 aa)
WEE1Wee1-like protein kinase. (646 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (416 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (314 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
RBL2RB transcriptional corepressor like 2. (1140 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (176 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (162 aa)
WEE2Wee1-like protein kinase. (567 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
PSMB8Proteasome subunit beta. (308 aa)
PSMB9Proteasome subunit beta. (219 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
ENSCSAP00000006740Uncharacterized protein. (525 aa)
ENSCSAP00000006748Uncharacterized protein. (550 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
E2F1E2F transcription factor 1. (437 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (383 aa)
LIN52Lin-52 DREAM MuvB core complex component. (84 aa)
PSMB6Proteasome subunit beta. (239 aa)
E2F5E2F transcription factor 5. (351 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
MAXMYC associated factor X. (103 aa)
PSMB7Proteasome subunit beta. (277 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
CCNHCyclin H; Belongs to the cyclin family. (323 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
CDC25ACell division cycle 25A. (523 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator subunit 1. (238 aa)
LIN9Lin-9 DREAM MuvB core complex component. (490 aa)
PTK6Tyrosine-protein kinase. (451 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
TFDP1Transcription factor. (410 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
CABLES1Cdk5 and Abl enzyme substrate 1. (630 aa)
RB1RB transcriptional corepressor 1. (928 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
PSME3Proteasome activator subunit 3. (267 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD9PDZ domain-containing protein. (223 aa)
UBCUncharacterized protein. (228 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB2Proteasome subunit beta. (201 aa)
CREBZFCREB/ATF bZIP transcription factor. (354 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSCSAP00000019055Transcription factor. (409 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.