STRINGSTRING
PSMB8 PSMB8 PSMB11 PSMB11 PSMC1 PSMC1 ENSCSAP00000018444 ENSCSAP00000018444 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017575 ENSCSAP00000017575 PSMB2 PSMB2 PSMA5 PSMA5 PSMB4 PSMB4 UBC UBC PSMD9 PSMD9 PSMB3 PSMB3 PSMD3 PSMD3 ATM ATM ZNF385C ZNF385C C17orf113 C17orf113 PSME3 PSME3 CCNA1 CCNA1 PSMA8 PSMA8 ENSCSAP00000013550 ENSCSAP00000013550 CCNA2 CCNA2 PSMC4 PSMC4 PSMC5 PSMC5 PSMB10 PSMB10 PSMD8 PSMD8 PSMD12 PSMD12 PSMD7 PSMD7 MDM2 MDM2 PSMA1 PSMA1 CCNE1 CCNE1 CDK3 CDK3 CDK2 CDK2 UBA52 UBA52 KXD1 KXD1 ZNF385A ZNF385A PSMC3 PSMC3 PSMD11 PSMD11 PSMD1 PSMD1 CDKN1B CDKN1B PSMD10 PSMD10 ENSCSAP00000005494 ENSCSAP00000005494 PSMB9 PSMB9 ENSCSAP00000006204 ENSCSAP00000006204 CHEK2 CHEK2 PHF20 PHF20 CDKN1A CDKN1A PSMF1 PSMF1 PSMD13 PSMD13 TP53 TP53 PSMC2 PSMC2 PSMB1 PSMB1 PSMD6 PSMD6 COP1 COP1 CCNE2 CCNE2 ZNF385B ZNF385B PSMB6 PSMB6 PSMD5 PSMD5 PSMB7 PSMB7 PSMD2 PSMD2 PSME4 PSME4 PCBP4 PCBP4 RPS27A RPS27A PSMA3 PSMA3 MDM4 MDM4 PSMA4 PSMA4 PSME1 PSME1 PSMB5 PSMB5 PSME2 PSME2 PSMC6 PSMC6 PSMA2 PSMA2 PSMA6 PSMA6 PSMD14 PSMD14 PSMA7 PSMA7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMB8Proteasome subunit beta. (308 aa)
PSMB11Proteasome subunit beta. (300 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
UBCUncharacterized protein. (228 aa)
PSMD9PDZ domain-containing protein. (223 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
ZNF385CZinc finger protein 385C. (424 aa)
C17orf113Chromosome 17 open reading frame 113. (580 aa)
PSME3Proteasome activator subunit 3. (267 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (416 aa)
CDK3Cyclin dependent kinase 3; Belongs to the protein kinase superfamily. (314 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (176 aa)
ZNF385AZinc finger protein 385A. (386 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMB9Proteasome subunit beta. (219 aa)
ENSCSAP00000006204FHA domain-containing protein. (214 aa)
CHEK2Protein kinase domain-containing protein. (318 aa)
PHF20PHD finger protein 20. (899 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
COP1COP1 E3 ubiquitin ligase. (759 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (383 aa)
ZNF385BZinc finger protein 385B. (369 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
PCBP4Poly(rC) binding protein 4. (403 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSME1Proteasome activator subunit 1. (238 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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