STRINGSTRING
U2AF1 U2AF1 SNRPE SNRPE CSTF2T CSTF2T LSM10 LSM10 LOC103224623-2 LOC103224623-2 NCBP2L NCBP2L ENSCSAP00000017627 ENSCSAP00000017627 TPRG1L TPRG1L SRRM1 SRRM1 SRSF4 SRSF4 MAGOH MAGOH SRSF11 SRSF11 U2AF2 U2AF2 RBM8A RBM8A CHTOP CHTOP ALYREF ALYREF SRSF9 SRSF9 ZNF473 ZNF473 CASC3 CASC3 SYMPK SYMPK SNRPF SNRPF UPF3B UPF3B THOC2 THOC2 CPSF4 CPSF4 ZC3H13 ZC3H13 THOC1 THOC1 WDR33 WDR33 PABPN1 PABPN1 ENSCSAP00000011985 ENSCSAP00000011985 SLBP SLBP CDC40 CDC40 CSTF1 CSTF1 ENSCSAP00000011248 ENSCSAP00000011248 ZC3H11A ZC3H11A SRSF6 SRSF6 SRSF5 SRSF5 SRSF7 SRSF7 THOC7 THOC7 ZNF318 ZNF318 CPSF2 CPSF2 NCBP1 NCBP1 SNRPB SNRPB SNRPD3 SNRPD3 LSM11 LSM11 PAPOLA PAPOLA SLU7 SLU7 CSTF2 CSTF2 WDR25 WDR25 SRSF3 SRSF3 THOC6 THOC6 THOC5 THOC5 THOC3 THOC3 TPRG1 TPRG1 LOC103224623 LOC103224623 NCBP2 NCBP2 DDX39B DDX39B CPSF1 CPSF1 LUZP4 LUZP4 FYTTD1 FYTTD1 CPSF3 CPSF3 CPSF7 CPSF7 DDX39A DDX39A CLP1 CLP1 POLDIP3 POLDIP3 SRSF1 SRSF1 SARNP SARNP ENSCSAP00000001539 ENSCSAP00000001539 NUDT21 NUDT21 SRSF2 SRSF2 FIP1L1 FIP1L1 CPSF4L CPSF4L U2AF1L4 U2AF1L4 CPSF6 CPSF6 DHX38 DHX38 C12orf50 C12orf50 PCF11 PCF11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
U2AF1Uncharacterized protein. (240 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa)
CSTF2TCleavage stimulation factor subunit 2 tau variant. (620 aa)
LSM10LSM10, U7 small nuclear RNA associated. (123 aa)
LOC103224623-2Protein mago nashi homolog 2. (148 aa)
NCBP2LNuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (153 aa)
ENSCSAP00000017627Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
TPRG1LTumor protein p63 regulated 1 like. (272 aa)
SRRM1Serine and arginine repetitive matrix 1. (587 aa)
SRSF4Serine and arginine rich splicing factor 4. (494 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
SRSF11Serine and arginine rich splicing factor 11. (483 aa)
U2AF2U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (471 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
CHTOPChromatin target of PRMT1. (249 aa)
ALYREFAly/REF export factor. (264 aa)
SRSF9Serine and arginine rich splicing factor 9. (221 aa)
ZNF473Zinc finger protein 473. (871 aa)
CASC3CASC3 exon junction complex subunit. (704 aa)
SYMPKSymplekin. (1274 aa)
SNRPFSmall nuclear ribonucleoprotein polypeptide F. (123 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
THOC2THO complex 2. (1593 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
ZC3H13Zinc finger CCCH-type containing 13. (1669 aa)
THOC1THO complex 1. (657 aa)
WDR33WD repeat domain 33. (1336 aa)
PABPN1Poly(A) binding protein nuclear 1. (306 aa)
ENSCSAP00000011985Uncharacterized protein. (503 aa)
SLBPStem-loop binding protein. (275 aa)
CDC40Cell division cycle 40. (579 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
ENSCSAP00000011248Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa)
ZC3H11AUncharacterized protein. (809 aa)
SRSF6Serine and arginine rich splicing factor 6. (343 aa)
SRSF5Serine and arginine rich splicing factor 5. (272 aa)
SRSF7Serine and arginine rich splicing factor 7. (239 aa)
THOC7THO complex 7. (204 aa)
ZNF318Zinc finger protein 318. (2099 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
SNRPBSmall nuclear ribonucleoprotein-associated protein. (231 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa)
LSM11LSM11, U7 small nuclear RNA associated. (360 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
SLU7SLU7 homolog, splicing factor. (490 aa)
CSTF2Cleavage stimulation factor subunit 2. (597 aa)
WDR25WD repeat domain 25. (536 aa)
SRSF3Serine and arginine rich splicing factor 3. (164 aa)
THOC6THO complex 6. (341 aa)
THOC5THO complex 5. (694 aa)
THOC3THO complex 3. (351 aa)
TPRG1Tumor protein p63 regulated 1. (279 aa)
LOC103224623Uncharacterized protein. (148 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (235 aa)
DDX39BDExD-box helicase 39B. (425 aa)
CPSF1Cleavage and polyadenylation specific factor 1. (1442 aa)
LUZP4Uncharacterized protein. (282 aa)
FYTTD1Forty-two-three domain containing 1. (318 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (631 aa)
CPSF7Cleavage and polyadenylation specific factor 7. (462 aa)
DDX39ADExD-box helicase 39A. (427 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
POLDIP3DNA polymerase delta interacting protein 3. (421 aa)
SRSF1Uncharacterized protein. (253 aa)
SARNPSAP domain containing ribonucleoprotein. (215 aa)
ENSCSAP00000001539RRM domain-containing protein. (298 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
SRSF2Serine and arginine rich splicing factor 2. (221 aa)
FIP1L1Fip1 domain-containing protein. (603 aa)
CPSF4LCleavage and polyadenylation specific factor 4 like. (180 aa)
U2AF1L4U2 small nuclear RNA auxiliary factor 1 like 4. (203 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (588 aa)
DHX38DEAH-box helicase 38. (1227 aa)
C12orf50Chromosome 12 open reading frame 50. (415 aa)
PCF11PCF11 cleavage and polyadenylation factor subunit. (1555 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.