STRINGSTRING
LPXN LPXN ERAS ERAS RNF222 RNF222 NRAS NRAS CSDE1 CSDE1 PXN PXN ELMOD1 ELMOD1 ARHGAP35 ARHGAP35 ELMOD2 ELMOD2 PTK6 PTK6 ELMOD3 ELMOD3 RHOA RHOA ELMO1 ELMO1 RASA1 RASA1 ELMO2 ELMO2 CRK CRK HRAS HRAS KRAS KRAS DOCK1 DOCK1 ELMO3 ELMO3 BCAR1 BCAR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
ERASES cell expressed Ras. (233 aa)
RNF222Ring finger protein 222. (220 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (844 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (591 aa)
ELMOD1ELMO domain containing 1. (334 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
ELMOD2ELMO domain containing 2. (293 aa)
PTK6Tyrosine-protein kinase. (451 aa)
ELMOD3ELMO domain containing 3. (365 aa)
RHOARas homolog family member A. (193 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1330 aa)
ELMO3Engulfment and cell motility 3. (720 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (870 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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