STRINGSTRING
SKP2 SKP2 HIVEP2 HIVEP2 ITGBL1 ITGBL1 ENSCSAP00000013550 ENSCSAP00000013550 YES1 YES1 RB1 RB1 SMURF1 SMURF1 ZNF521 ZNF521 PSMA8 PSMA8 SMAD4 SMAD4 SMAD1 SMAD1 PSME3 PSME3 FBXW7 FBXW7 YAP1 YAP1 MMP13 MMP13 HAND2 HAND2 PSMD3 PSMD3 PSMB3 PSMB3 PSMD9 PSMD9 BGLAP BGLAP UBC UBC PSMB4 PSMB4 PSMA5 PSMA5 HIVEP3 HIVEP3 PSMB2 PSMB2 HES4 HES4 CREBZF CREBZF CDK1 CDK1 ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 TWIST2 TWIST2 ENSCSAP00000018444 ENSCSAP00000018444 PSMC1 PSMC1 SP7 SP7 TWIST1 TWIST1 PSMB11 PSMB11 PPARGC1B PPARGC1B PSMB1 PSMB1 SOX8 SOX8 AR AR PSMD6 PSMD6 STAT1 STAT1 STUB1 STUB1 NR3C1 NR3C1 HDAC3 HDAC3 RUNX2 RUNX2 DLX5 DLX5 WWP1 WWP1 PSMB6 PSMB6 UCMA UCMA PSMD5 PSMD5 HDAC6 HDAC6 SMAD6 SMAD6 HEY1 HEY1 BMP2 BMP2 ENSCSAP00000004608 ENSCSAP00000004608 ENSCSAP00000003769 ENSCSAP00000003769 HIVEP1 HIVEP1 ESRRA ESRRA GSK3B GSK3B CUL1 CUL1 PSMD1 PSMD1 PSMD11 PSMD11 MAPK3 MAPK3 HDAC4 HDAC4 PPM1D PPM1D RBX1 RBX1 PSMC3 PSMC3 ZNF423 ZNF423 ITGA5 ITGA5 CCND1 CCND1 PSMD13 PSMD13 SATB2 SATB2 WWTR1 WWTR1 PSMC2 PSMC2 SOX30 SOX30 ENSCSAP00000005494 ENSCSAP00000005494 PSMD10 PSMD10 PSMA1 PSMA1 HES1 HES1 RUNX1 RUNX1 IHH IHH CBFB CBFB AKT2 AKT2 PSMC4 PSMC4 PSMC5 PSMC5 PSMB10 PSMB10 PSMD8 PSMD8 PSMD12 PSMD12 PSMD7 PSMD7 SOX9 SOX9 CDK4 CDK4 PSMF1 PSMF1 CDKN1A CDKN1A AKT1 AKT1 MSX2 MSX2 PSMB9 PSMB9 PSMB8 PSMB8 AKT3 AKT3 COL1A1 COL1A1 UBA52 UBA52 PSMB7 PSMB7 SP8 SP8 SKP1 SKP1 MAPK1 MAPK1 PSMD2 PSMD2 SRC SRC PSME4 PSME4 RPS27A RPS27A ESR1 ESR1 PSMA3 PSMA3 SP9 SP9 LGALS3 LGALS3 ABL1 ABL1 PSMA4 PSMA4 PSMC6 PSMC6 GLI3 GLI3 PSMA2 PSMA2 ZNF831 ZNF831 PSMD14 PSMD14 PSMA7 PSMA7 CCNB1 CCNB1 PSME2 PSME2 PSMB5 PSMB5 PSME1 PSME1 HEY2 HEY2 NKX3-2 NKX3-2 PPARGC1A PPARGC1A GLI2 GLI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SKP2S-phase kinase associated protein 2. (424 aa)
HIVEP2Human immunodeficiency virus type I enhancer binding protein 2. (2449 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
YES1Tyrosine-protein kinase. (543 aa)
RB1RB transcriptional corepressor 1. (928 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
ZNF521Zinc finger protein 521. (1311 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
PSME3Proteasome activator subunit 3. (267 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
YAP1Yes associated protein 1. (508 aa)
MMP13Matrix metallopeptidase 13. (471 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD9PDZ domain-containing protein. (223 aa)
BGLAPOsteocalcin; Binds strongly to apatite and calcium. (100 aa)
UBCUncharacterized protein. (228 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2406 aa)
PSMB2Proteasome subunit beta. (201 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
CREBZFCREB/ATF bZIP transcription factor. (354 aa)
CDK1Protein kinase domain-containing protein. (297 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
TWIST2Twist family bHLH transcription factor 2. (160 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
SP7Sp7 transcription factor. (431 aa)
TWIST1Twist family bHLH transcription factor 1. (200 aa)
PSMB11Proteasome subunit beta. (300 aa)
PPARGC1BPPARG coactivator 1 beta. (996 aa)
PSMB1Proteasome subunit beta. (241 aa)
SOX8SRY-box transcription factor 8. (446 aa)
ARAndrogen receptor. (900 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (776 aa)
HDAC3Hist_deacetyl domain-containing protein. (266 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (450 aa)
DLX5Distal-less homeobox 5. (289 aa)
WWP1WW domain containing E3 ubiquitin protein ligase 1. (684 aa)
PSMB6Proteasome subunit beta. (239 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (140 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
HDAC6Histone deacetylase 6. (1215 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ENSCSAP00000004608RRM domain-containing protein. (147 aa)
ENSCSAP00000003769Uncharacterized protein. (473 aa)
HIVEP1Uncharacterized protein. (2175 aa)
ESRRAEstrogen related receptor alpha. (422 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1088 aa)
PPM1DProtein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
RBX1Ring-box 1. (108 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
ZNF423Zinc finger protein 423. (1284 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
SATB2DNA-binding protein SATB. (733 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
SOX30SRY-box transcription factor 30. (754 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (456 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
CBFBCore-binding factor subunit beta. (187 aa)
AKT2Non-specific serine/threonine protein kinase. (535 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MSX2Msh homeobox 2. (267 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (308 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
PSMB7Proteasome subunit beta. (277 aa)
SP8Sp8 transcription factor. (507 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SRCTyrosine-protein kinase. (633 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ESR1Estrogen receptor 1. (487 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
SP9Sp9 transcription factor. (486 aa)
LGALS3Galectin. (248 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
GLI3GLI family zinc finger 3. (1459 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
ZNF831Zinc finger protein 831. (1676 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (429 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator subunit 1. (238 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
NKX3-2NK3 homeobox 2. (333 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
GLI2GLI family zinc finger 2. (1554 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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