STRINGSTRING
EP300 EP300 CBFB CBFB PSMC4 PSMC4 PSMC5 PSMC5 PSMB10 PSMB10 SMURF2 SMURF2 PSMD8 PSMD8 PSMD12 PSMD12 PSMD7 PSMD7 MDM2 MDM2 PSMA1 PSMA1 UBA52 UBA52 PSMC3 PSMC3 PSMD11 PSMD11 PSMD1 PSMD1 PSMD10 PSMD10 ENSCSAP00000005494 ENSCSAP00000005494 PSMB8 PSMB8 PSMB9 PSMB9 PSMF1 PSMF1 PSMD13 PSMD13 PSMC2 PSMC2 PSMB1 PSMB1 PSMD6 PSMD6 FNDC3B FNDC3B PSMB6 PSMB6 PSMD5 PSMD5 PSMB7 PSMB7 PSMD2 PSMD2 SRC SRC RPS27A RPS27A PSMA3 PSMA3 PSMA4 PSMA4 PSMC6 PSMC6 PSMA2 PSMA2 PSMA6 PSMA6 PSMD14 PSMD14 PSMA7 PSMA7 PSME2 PSME2 PSMB5 PSMB5 PSME1 PSME1 ENSCSAP00000013550 ENSCSAP00000013550 FNDC3A FNDC3A SMURF1 SMURF1 TGFB1 TGFB1 PSME3 PSME3 PSMD3 PSMD3 PSMB3 PSMB3 PSMD9 PSMD9 UBC UBC PSMB4 PSMB4 PSMA5 PSMA5 PSMB2 PSMB2 RUNX3 RUNX3 CREBZF CREBZF ENSCSAP00000017575 ENSCSAP00000017575 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000018444 ENSCSAP00000018444 PSMC1 PSMC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EP300E1A binding protein p300. (2416 aa)
CBFBCore-binding factor subunit beta. (187 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMB10Proteasome subunit beta. (273 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (474 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMB8Proteasome subunit beta. (308 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
FNDC3BFibronectin type III domain containing 3B. (1204 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
SRCTyrosine-protein kinase. (633 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSME2Proteasome activator subunit 2. (253 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME1Proteasome activator subunit 1. (238 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PSME3Proteasome activator subunit 3. (267 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD9PDZ domain-containing protein. (223 aa)
UBCUncharacterized protein. (228 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB2Proteasome subunit beta. (201 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
CREBZFCREB/ATF bZIP transcription factor. (354 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: medium (46%) [HD]