STRINGSTRING
NRG1 NRG1 ERAS ERAS SOCS3 SOCS3 ENSCSAP00000018444 ENSCSAP00000018444 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017575 ENSCSAP00000017575 RNF222 RNF222 KHDRBS1 KHDRBS1 SFPQ SFPQ NRAS NRAS CSDE1 CSDE1 UBC UBC KRAS KRAS STAT3 STAT3 ELMOD2 ELMOD2 PSPC1 PSPC1 SRMS SRMS PTK6 PTK6 ELMOD3 ELMOD3 EGFR EGFR DOK1 DOK1 PTPN1 PTPN1 RHOA RHOA ELMO1 ELMO1 RASA1 RASA1 ELMO2 ELMO2 NRG4 NRG4 ENSCSAP00000010546 ENSCSAP00000010546 RPS27A RPS27A HIF1A HIF1A CRK CRK GPNMB GPNMB EPAS1 EPAS1 KHDRBS2 KHDRBS2 PELP1 PELP1 NRG2 NRG2 HBEGF HBEGF NR3C1 NR3C1 ENSCSAP00000007573 ENSCSAP00000007573 NONO NONO HRAS HRAS STAP2 STAP2 KHDRBS3 KHDRBS3 AKT1 AKT1 NRG3 NRG3 ENSCSAP00000005731 ENSCSAP00000005731 ERBB4 ERBB4 CCND1 CCND1 CDKN1B CDKN1B BTC BTC EREG EREG CCNE1 CCNE1 ERBB3 ERBB3 CDK2 CDK2 UBA52 UBA52 KXD1 KXD1 DOCK1 DOCK1 LPXN LPXN LRRK2 LRRK2 CDK4 CDK4 BCAR1 BCAR1 ELMO3 ELMO3 EGF EGF ARAP1 ARAP1 PXN PXN CBL CBL ERBB2 ERBB2 ELMOD1 ELMOD1 ARHGAP35 ARHGAP35
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRG1Neuregulin 1. (467 aa)
ERASES cell expressed Ras. (233 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
RNF222Ring finger protein 222. (220 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (547 aa)
SFPQSplicing factor proline and glutamine rich. (708 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (844 aa)
UBCUncharacterized protein. (228 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
ELMOD2ELMO domain containing 2. (293 aa)
PSPC1Paraspeckle component 1. (267 aa)
SRMSTyrosine-protein kinase. (488 aa)
PTK6Tyrosine-protein kinase. (451 aa)
ELMOD3ELMO domain containing 3. (365 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
DOK1Docking protein 1. (574 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (435 aa)
RHOARas homolog family member A. (193 aa)
ELMO1Engulfment and cell motility 1. (727 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
ELMO2Engulfment and cell motility 2. (720 aa)
NRG4Neuregulin 4. (117 aa)
ENSCSAP00000010546RRM domain-containing protein. (388 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
GPNMBGlycoprotein nmb. (560 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (276 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1222 aa)
NRG2Neuregulin 2. (850 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
NR3C1Nuclear receptor subfamily 3 group C member 1. (776 aa)
ENSCSAP00000007573RRM domain-containing protein. (201 aa)
NONONOPS domain-containing protein. (258 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
STAP2Signal transducing adaptor family member 2. (420 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (325 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
NRG3Uncharacterized protein. (376 aa)
ENSCSAP00000005731Protein kinase domain-containing protein. (479 aa)
ERBB4Protein kinase domain-containing protein. (622 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
BTCBetacellulin. (171 aa)
EREGEpiregulin. (171 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (416 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1342 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
KXD1KxDL motif containing 1. (176 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1330 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (870 aa)
ELMO3Engulfment and cell motility 3. (720 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
ARAP1ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1. (1205 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (591 aa)
CBLCbl proto-oncogene. (907 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
ELMOD1ELMO domain containing 1. (334 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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