STRINGSTRING
ENSCSAP00000017575 ENSCSAP00000017575 EGF EGF WWP2 WWP2 PSENEN PSENEN NEURL1 NEURL1 NOTCH3 NOTCH3 DLL4 DLL4 JAG2 JAG2 NEURL1B NEURL1B DLL1 DLL1 ADAM10 ADAM10 APH1B APH1B PSEN1 PSEN1 JAG1 JAG1 RPS27A RPS27A TACC3 TACC3 EGFR EGFR PSEN2 PSEN2 MIB1 MIB1 APH1A APH1A ENSCSAP00000017765 ENSCSAP00000017765 NCSTN NCSTN YBX1 YBX1 MIB2 MIB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
NOTCH3Notch receptor 3. (1980 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (555 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
PSEN1Presenilin 1. (467 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (839 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
NCSTNNicastrin. (709 aa)
YBX1Y-box binding protein 1. (255 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (955 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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