STRINGSTRING
PSENEN PSENEN PSMC1 PSMC1 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017575 ENSCSAP00000017575 HES4 HES4 HES5 HES5 PSMB2 PSMB2 PSMA5 PSMA5 NOTCH2 NOTCH2 PSMB4 PSMB4 PSMD9 PSMD9 NCSTN NCSTN PSMB3 PSMB3 PSMD3 PSMD3 KAT2A KAT2A MAML2 MAML2 FBXW7 FBXW7 PSME3 PSME3 APH1A APH1A ENSCSAP00000013550 ENSCSAP00000013550 RBPJ RBPJ PSEN2 PSEN2 HEY2 HEY2 PSME1 PSME1 PSMB5 PSMB5 PSME2 PSME2 NOTCH1 NOTCH1 PSMA7 PSMA7 PSMD14 PSMD14 TACC3 TACC3 PSMA2 PSMA2 PSMC6 PSMC6 PSMA4 PSMA4 PSMA3 PSMA3 RPS27A RPS27A PSMD2 PSMD2 JAG1 JAG1 SKP1 SKP1 CRB1 CRB1 PSMB7 PSMB7 HEY1 HEY1 SMAD3 SMAD3 PSMD5 PSMD5 PSMB6 PSMB6 PSEN1 PSEN1 APH1B APH1B YWHAZ YWHAZ ADAM10 ADAM10 PSMD6 PSMD6 PSMB1 PSMB1 SNW1 SNW1 PSMC2 PSMC2 PSMD13 PSMD13 PSMF1 PSMF1 KAT2B KAT2B AKT1 AKT1 CREBBP CREBBP PSMB9 PSMB9 PSMB8 PSMB8 NOTCH4 NOTCH4 ENSCSAP00000005494 ENSCSAP00000005494 PSMD10 PSMD10 HES1 HES1 MAML1 MAML1 FLT4 FLT4 DLL4 DLL4 MAMLD1 MAMLD1 CUL1 CUL1 PSMD1 PSMD1 PSMD11 PSMD11 RBX1 RBX1 EP300 EP300 PSMC3 PSMC3 PSMA1 PSMA1 PSMD7 PSMD7 PSMD12 PSMD12 PSMD8 PSMD8 PSMB10 PSMB10 PSMC5 PSMC5 PSMC4 PSMC4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
PSMB2Proteasome subunit beta. (201 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
NOTCH2Notch receptor 2. (2471 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
PSMD9PDZ domain-containing protein. (223 aa)
NCSTNNicastrin. (709 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
MAML2Mastermind like transcriptional coactivator 2. (923 aa)
FBXW7F-box and WD repeat domain containing 7. (707 aa)
PSME3Proteasome activator subunit 3. (267 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (357 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
PSME1Proteasome activator subunit 1. (238 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME2Proteasome activator subunit 2. (253 aa)
NOTCH1Notch receptor 1. (2555 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (839 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
CRB1Crumbs cell polarity complex component 1. (1335 aa)
PSMB7Proteasome subunit beta. (277 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSEN1Presenilin 1. (467 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PSMB1Proteasome subunit beta. (241 aa)
SNW1SNW domain containing 1. (536 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
KAT2BLysine acetyltransferase 2B. (675 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CREBBPCREB binding protein. (2417 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (308 aa)
NOTCH4Notch receptor 4. (1994 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
MAML1Mastermind like transcriptional coactivator 1. (790 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1361 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
MAMLD1Mastermind like domain containing 1. (810 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
RBX1Ring-box 1. (108 aa)
EP300E1A binding protein p300. (2416 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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