STRINGSTRING
NCOR2 NCOR2 ENSCSAP00000000163 ENSCSAP00000000163 TNRC6B TNRC6B MECP2 MECP2 HIPK2 HIPK2 NCOR1 NCOR1 AGO2 AGO2 CREB1 CREB1 AURKB AURKB CAMK2A CAMK2A HDAC3 HDAC3 TBL1XR1 TBL1XR1 SIN3A SIN3A CAMK4 CAMK4 TBL1X TBL1X CAMK2B CAMK2B HDAC2 HDAC2 FOXG1 FOXG1 ENSCSAP00000017750 ENSCSAP00000017750 HDAC1 HDAC1 AGO4 AGO4 AGO1 AGO1 AGO3 AGO3 MOV10 MOV10 ENSCSAP00000016053 ENSCSAP00000016053 HTT HTT LBR LBR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCOR2Nuclear receptor corepressor 2. (2521 aa)
ENSCSAP00000000163Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (489 aa)
TNRC6BTrinucleotide repeat containing adaptor 6B. (1773 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (479 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
NCOR1Nuclear receptor corepressor 1. (2445 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (904 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
HDAC3Hist_deacetyl domain-containing protein. (266 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV. (614 aa)
TBL1XTransducin beta like 1 X-linked. (572 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
FOXG1Forkhead box G1. (490 aa)
ENSCSAP00000017750Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
MOV10Mov10 RISC complex RNA helicase. (1003 aa)
ENSCSAP00000016053Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
HTTHuntingtin. (3133 aa)
LBRLamin B receptor. (622 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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