STRINGSTRING
KRAS KRAS HRAS HRAS FRS3 FRS3 SOS1 SOS1 PTPN11 PTPN11 NRAS NRAS BDNF BDNF ERAS ERAS NTF4 NTF4 FRS2 FRS2 GRB2 GRB2 NTRK2 NTRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRASKRAS proto-oncogene, GTPase. (189 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
FRS3Fibroblast growth factor receptor substrate 3. (492 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
ERASES cell expressed Ras. (233 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (210 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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