STRINGSTRING
PSMD2 PSMD2 PSMB11 PSMB11 PSMC1 PSMC1 ENSCSAP00000018444 ENSCSAP00000018444 AMER1 AMER1 ENSCSAP00000017765 ENSCSAP00000017765 ENSCSAP00000017575 ENSCSAP00000017575 CREBZF CREBZF PGD PGD MUL1 MUL1 SESN2 SESN2 PSMB2 PSMB2 PRDX1 PRDX1 GCLM GCLM PSMA5 PSMA5 PSMB4 PSMB4 UBC UBC PSMD9 PSMD9 MAFG MAFG NPLOC4 NPLOC4 NFE2L1 NFE2L1 PSMB3 PSMB3 PSMD3 PSMD3 TXNRD1 TXNRD1 MAP1LC3B MAP1LC3B PSME3 PSME3 BRCA1 BRCA1 SLC7A11 SLC7A11 ENSCSAP00000014414 ENSCSAP00000014414 PSMA8 PSMA8 MAFK MAFK ENSCSAP00000013550 ENSCSAP00000013550 ME1 ME1 BACH2 BACH2 SKP2 SKP2 PSME1 PSME1 PSMB5 PSMB5 PSME2 PSME2 KLHL18 KLHL18 NOTCH1 NOTCH1 GSR GSR PSMA7 PSMA7 PSMD14 PSMD14 PSMA6 PSMA6 PSMA2 PSMA2 SESN1 SESN1 FBXL17 FBXL17 PSMC6 PSMC6 PSMA4 PSMA4 PSMA3 PSMA3 NFE2L2 NFE2L2 NFE2L3 NFE2L3 RPS27A RPS27A PSME4 PSME4 SKP1 SKP1 PSMB7 PSMB7 PSMD5 PSMD5 GCLC GCLC PRKCD PRKCD TKT TKT PSMB6 PSMB6 PSMD6 PSMD6 PSMB1 PSMB1 PSMC2 PSMC2 UFD1 UFD1 PSMD13 PSMD13 TALDO1 TALDO1 PSMF1 PSMF1 ENSCSAP00000006748 ENSCSAP00000006748 ENSCSAP00000006740 ENSCSAP00000006740 CSNK2A1 CSNK2A1 CDKN1A CDKN1A SPATA5L1 SPATA5L1 VCP VCP MYC MYC IDH1 IDH1 AKT1 AKT1 CREBBP CREBBP MTFP1 MTFP1 PSMB9 PSMB9 PSMB8 PSMB8 AKT3 AKT3 ENSCSAP00000005494 ENSCSAP00000005494 BACH1 BACH1 PSMD10 PSMD10 TRIM58 TRIM58 UBXN7 UBXN7 SQSTM1 SQSTM1 DPP3 DPP3 HMOX1 HMOX1 TXNRD3 TXNRD3 CUL3 CUL3 GSK3B GSK3B KEAP1 KEAP1 CUL1 CUL1 PALB2 PALB2 PSMD1 PSMD1 G6PD G6PD PSMD11 PSMD11 ATF4 ATF4 RBX1 RBX1 EP300 EP300 PSMC3 PSMC3 BTRC BTRC KXD1 KXD1 UBA52 UBA52 CSNK2A2 CSNK2A2 PSMA1 PSMA1 TRIM21 TRIM21 PSMD7 PSMD7 PSMD12 PSMD12 NQO1 NQO1 PSMD8 PSMD8 PSMB10 PSMB10 PSMC5 PSMC5 PSMC4 PSMC4 AKT2 AKT2 SPATA5 SPATA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PSMD226S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family. (908 aa)
PSMB11Proteasome subunit beta. (300 aa)
PSMC1AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa)
ENSCSAP00000018444Ubiquitin-like domain-containing protein. (127 aa)
AMER1APC membrane recruitment protein 1. (1134 aa)
ENSCSAP00000017765Ubiquitin-like domain-containing protein. (155 aa)
ENSCSAP00000017575Ubiquitin-like domain-containing protein. (156 aa)
CREBZFCREB/ATF bZIP transcription factor. (354 aa)
PGDPhosphogluconate dehydrogenase. (311 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
SESN2Sestrin 2. (480 aa)
PSMB2Proteasome subunit beta. (201 aa)
PRDX1Peroxiredoxin 1. (199 aa)
GCLMGlutamate-cysteine ligase modifier subunit. (274 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (264 aa)
UBCUncharacterized protein. (228 aa)
PSMD9PDZ domain-containing protein. (223 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
NPLOC4NPL4 homolog, ubiquitin recognition factor. (608 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (772 aa)
PSMB3Proteasome subunit beta. (205 aa)
PSMD3Proteasome 26S subunit, non-ATPase 3. (534 aa)
TXNRD1Thioredoxin reductase 1. (497 aa)
MAP1LC3BUncharacterized protein. (125 aa)
PSME3Proteasome activator subunit 3. (267 aa)
BRCA1Uncharacterized protein. (663 aa)
SLC7A11Solute carrier family 7 member 11. (501 aa)
ENSCSAP00000014414AAA_lid_3 domain-containing protein. (111 aa)
PSMA8Proteasome subunit alpha type. (250 aa)
MAFKMAF bZIP transcription factor K. (156 aa)
ENSCSAP00000013550PROTEASOME_ALPHA_1 domain-containing protein. (218 aa)
ME1Malic enzyme. (572 aa)
BACH2BTB domain and CNC homolog 2. (842 aa)
SKP2S-phase kinase associated protein 2. (424 aa)
PSME1Proteasome activator subunit 1. (238 aa)
PSMB5Proteasome subunit beta. (263 aa)
PSME2Proteasome activator subunit 2. (253 aa)
KLHL18Kelch like family member 18. (574 aa)
NOTCH1Notch receptor 1. (2555 aa)
GSRGlutathione-disulfide reductase. (391 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
PSMD14Proteasome 26S subunit, non-ATPase 14. (310 aa)
PSMA6Proteasome subunit alpha type. (252 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
SESN1Sestrin 1. (492 aa)
FBXL17F-box and leucine rich repeat protein 17. (583 aa)
PSMC6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (403 aa)
PSMA4Proteasome subunit alpha type. (261 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
NFE2L3Nuclear factor, erythroid 2 like 3. (693 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
PSME4Proteasome activator subunit 4. (1843 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (163 aa)
PSMB7Proteasome subunit beta. (277 aa)
PSMD5Proteasome 26S subunit, non-ATPase 5. (504 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (638 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
TKTTransketolase. (623 aa)
PSMB6Proteasome subunit beta. (239 aa)
PSMD6Proteasome 26S subunit, non-ATPase 6. (412 aa)
PSMB1Proteasome subunit beta. (241 aa)
PSMC2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (433 aa)
UFD1Ubiquitin recognition factor in ER associated degradation 1. (307 aa)
PSMD13Proteasome 26S subunit, non-ATPase 13. (377 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
PSMF1Proteasome inhibitor subunit 1. (271 aa)
ENSCSAP00000006748Uncharacterized protein. (550 aa)
ENSCSAP00000006740Uncharacterized protein. (525 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
SPATA5L1Spermatogenesis associated 5 like 1. (753 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
CREBBPCREB binding protein. (2417 aa)
MTFP1Mitochondrial fission process 1. (166 aa)
PSMB9Proteasome subunit beta. (219 aa)
PSMB8Proteasome subunit beta. (308 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
ENSCSAP00000005494ANK_REP_REGION domain-containing protein. (217 aa)
BACH1BTB domain and CNC homolog 1. (736 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (226 aa)
TRIM58Tripartite motif containing 58. (342 aa)
UBXN7UBX domain protein 7. (521 aa)
SQSTM1Sequestosome 1. (440 aa)
DPP3Dipeptidyl peptidase 3; Belongs to the peptidase M49 family. (740 aa)
HMOX1Heme oxygenase 1. (288 aa)
TXNRD3Thioredoxin reductase 3. (573 aa)
CUL3Cullin 3; Belongs to the cullin family. (768 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
KEAP1Kelch like ECH associated protein 1. (624 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
PALB2Partner and localizer of BRCA2. (1183 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (958 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
PSMD11Proteasome 26S subunit, non-ATPase 11. (422 aa)
ATF4Activating transcription factor 4. (351 aa)
RBX1Ring-box 1. (108 aa)
EP300E1A binding protein p300. (2416 aa)
PSMC3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (265 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
KXD1KxDL motif containing 1. (176 aa)
UBA52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
TRIM21Tripartite motif containing 21. (475 aa)
PSMD7Proteasome 26S subunit, non-ATPase 7. (324 aa)
PSMD12Proteasome 26S subunit, non-ATPase 12. (456 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (255 aa)
PSMD8Proteasome 26S subunit, non-ATPase 8. (287 aa)
PSMB10Proteasome subunit beta. (273 aa)
PSMC5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (406 aa)
PSMC4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa)
AKT2Non-specific serine/threonine protein kinase. (535 aa)
SPATA5Uncharacterized protein. (789 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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