STRINGSTRING
UGT2B4 UGT2B4 UGT2B15 UGT2B15 ENSCSAP00000001583 ENSCSAP00000001583 ENSCSAP00000001586 ENSCSAP00000001586 CDK2 CDK2 ENSCSAP00000002604 ENSCSAP00000002604 DNMT1 DNMT1 KRAS KRAS ALDH3A1 ALDH3A1 ALDH3A2 ALDH3A2 SIM2 SIM2 ALDH3B1 ALDH3B1 VDAC2 VDAC2 CCND1 CCND1 CYP1B1 CYP1B1 E2F1 E2F1 CYP1A1 CYP1A1 SIM1 SIM1 DHFR DHFR EGFR EGFR UGT3A2 UGT3A2 UGT3A1 UGT3A1 CCNA1 CCNA1 ARNT ARNT MCL1 MCL1 APAF1 APAF1 CASP3 CASP3 HDAC1 HDAC1 JUND JUND MDM2 MDM2 UGT2A1 UGT2A1 CCNA2 CCNA2 NQO1 NQO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UGT2B4UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (528 aa)
UGT2B15UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (530 aa)
ENSCSAP00000001583UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
ENSCSAP00000001586UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (529 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
ENSCSAP00000002604UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1616 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
SIM2SIM bHLH transcription factor 2. (667 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
VDAC2Voltage dependent anion channel 2. (255 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
E2F1E2F transcription factor 1. (437 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
SIM1SIM bHLH transcription factor 1. (766 aa)
DHFRDihydrofolate reductase; Belongs to the dihydrofolate reductase family. (187 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
UGT3A2UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (523 aa)
UGT3A1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (523 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (465 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (789 aa)
MCL1MCL1 apoptosis regulator, BCL2 family member. (350 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (348 aa)
MDM2E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (491 aa)
UGT2A1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (527 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
NQO1NAD(P)H quinone dehydrogenase 1. (255 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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