STRINGSTRING
MAPT MAPT ADAM10 ADAM10 PSEN1 PSEN1 GTF2H5 GTF2H5 PCNA PCNA SNAP25 SNAP25 MAOB MAOB MAOA MAOA ACHE ACHE APAF1 APAF1 CASP3 CASP3 CRH CRH DYNLL1 DYNLL1 ENSCSAP00000018835 ENSCSAP00000018835 UCN UCN SNCA SNCA UBE3A UBE3A RAD23A RAD23A GAPDH GAPDH DCTN4 DCTN4 NLGN3 NLGN3 KIF5B KIF5B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAPTMicrotubule-associated protein. (861 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
PSEN1Presenilin 1. (467 aa)
GTF2H5General transcription factor IIH subunit 5. (71 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
MAOBAmine oxidase. (520 aa)
MAOAAmine oxidase. (527 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (614 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1248 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
CRHCorticotropin releasing hormone. (196 aa)
DYNLL1Dynein light chain. (89 aa)
ENSCSAP00000018835Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
UCNUrocortin. (124 aa)
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (872 aa)
RAD23ARAD23 homolog A, nucleotide excision repair protein. (363 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
DCTN4Uncharacterized protein. (467 aa)
NLGN3Neuroligin 3. (848 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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