STRINGSTRING
NCF4 NCF4 CXCL13 CXCL13 MAP3K14 MAP3K14 ANXA5 ANXA5 LGR5 LGR5 IL22 IL22 IFNG IFNG TRAF6 TRAF6 CCL20 CCL20 GP2 GP2 WRN WRN RSPO3 RSPO3 WNT3A WNT3A TCF21 TCF21 IL1B IL1B ALDH1A3 ALDH1A3 IL22RA2 IL22RA2 RELB RELB PGLYRP1 PGLYRP1 NES NES S100A4 S100A4 IFI6 IFI6 NOG NOG UBD UBD ALDH1A1 ALDH1A1 RARS1 RARS1 IFITM1 IFITM1 SOX8 SOX8 STING1 STING1 SH3KBP1 SH3KBP1 GFI1B GFI1B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCF4Neutrophil cytosolic factor 4. (294 aa)
CXCL13C-X-C motif chemokine. (109 aa)
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (947 aa)
ANXA5Annexin. (320 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (812 aa)
IL22Interleukin 22. (179 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
CCL20C-C motif chemokine. (96 aa)
GP2Glycoprotein 2. (534 aa)
WRNWRN RecQ like helicase. (1399 aa)
RSPO3R-spondin 3. (273 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
TCF21Transcription factor 21. (179 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (393 aa)
IL22RA2Interleukin 22 receptor subunit alpha 2. (263 aa)
RELBRELB proto-oncogene, NF-kB subunit. (440 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
NESNestin; Belongs to the intermediate filament family. (1619 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
IFI6Interferon alpha inducible protein 6. (130 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
UBDUbiquitin D. (165 aa)
ALDH1A1Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa)
RARS1Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (660 aa)
IFITM1Uncharacterized protein. (125 aa)
SOX8SRY-box transcription factor 8. (446 aa)
STING1Transmembrane protein 173. (379 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (690 aa)
GFI1BGrowth factor independent 1B transcriptional repressor. (331 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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