STRINGSTRING
DYNLT1 DYNLT1 STAT1 STAT1 LOC103232061 LOC103232061 PABPC1 PABPC1 NEDD4 NEDD4 RAB27A RAB27A KLC4 KLC4 LMNB2 LMNB2 CCND3 CCND3 TSC2 TSC2 ESYT3 ESYT3 CAV1 CAV1 IRF7 IRF7 NCL NCL CD63 CD63 TRAF6 TRAF6 EIF4B EIF4B RAD50 RAD50 ENSCSAP00000009816 ENSCSAP00000009816 RNASEL RNASEL ATRX ATRX SP100 SP100 CCNT1 CCNT1 DNM2 DNM2 TBK1 TBK1 SUMO2 SUMO2 GRB2 GRB2 H3F3B H3F3B CLOCK CLOCK ESYT1 ESYT1 XPO6 XPO6 FEN1 FEN1 CD80 CD80 SUMO3 SUMO3 KLC2 KLC2 CSNK2B CSNK2B USP7 USP7 CENPA CENPA FADD FADD IFNA2 IFNA2 CHEK2 CHEK2 CD4 CD4 CASP8 CASP8 TLR1 TLR1 LOC103230365 LOC103230365 ENSCSAP00000018835 ENSCSAP00000018835 LOC103221619 LOC103221619 H3C11 H3C11 LOC103215048 LOC103215048 CENPB CENPB PRKACG PRKACG ENSCSAP00000017986 ENSCSAP00000017986 SUMO1 SUMO1 PABPC5 PABPC5 LOC103232262 LOC103232262 PABPC1L2B PABPC1L2B LOC103247786 LOC103247786 ENSCSAP00000017749 ENSCSAP00000017749 TLR2 TLR2 CENPS CENPS LCK LCK HDAC1 HDAC1 PABPC4 PABPC4 PRKACB PRKACB ULK1 ULK1 LMNA LMNA TIRAP TIRAP CD1D CD1D TK1 TK1 IFI16 IFI16 AIM2 AIM2 IRF3 IRF3 NECTIN1 NECTIN1 CBL CBL ATM ATM CASP3 CASP3 BECN1 BECN1 EIF4H EIF4H DYNLT3 DYNLT3 BCLAF1 BCLAF1 DOK2 DOK2 CCNT2 CCNT2 TRIM23 TRIM23 CDK7 CDK7 GZMB GZMB HDAC2 HDAC2 ATG5 ATG5 LMNB1 LMNB1 MYD88 MYD88 PABPC1L PABPC1L CGAS CGAS CDK9 CDK9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DYNLT1Dynein light chain Tctex-type 1. (122 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
LOC103232061Histone domain-containing protein. (136 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
NEDD4E3 ubiquitin-protein ligase. (900 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
KLC4Kinesin light chain 4. (633 aa)
LMNB2Lamin B2; Belongs to the intermediate filament family. (621 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
TSC2TSC complex subunit 2. (1806 aa)
ESYT3Extended synaptotagmin 3. (875 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
IRF7Interferon regulatory factor 7. (506 aa)
NCLNucleolin. (463 aa)
CD63Tetraspanin. (238 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
EIF4BEukaryotic translation initiation factor 4B. (611 aa)
RAD50Zinc-hook domain-containing protein. (1312 aa)
ENSCSAP00000009816Histone H3; Belongs to the histone H3 family. (136 aa)
RNASELRibonuclease L. (741 aa)
ATRXATRX chromatin remodeler. (2459 aa)
SP100SP100 nuclear antigen. (851 aa)
CCNT1Cyclin T1; Belongs to the cyclin family. (728 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
TBK1TANK binding kinase 1. (729 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
CLOCKClock circadian regulator. (847 aa)
ESYT1Extended synaptotagmin 1. (1104 aa)
XPO6Exportin 6. (783 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (346 aa)
CD80Ig-like domain-containing protein. (138 aa)
SUMO3Small ubiquitin-related modifier. (110 aa)
KLC2Kinesin light chain 2. (483 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (228 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1102 aa)
CENPACentromere protein A. (138 aa)
FADDDED domain-containing protein. (189 aa)
IFNA2Interferon alpha 2. (190 aa)
CHEK2Protein kinase domain-containing protein. (318 aa)
CD4CD4 molecule. (560 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (496 aa)
TLR1Toll like receptor 1; Belongs to the Toll-like receptor family. (786 aa)
LOC103230365Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCSAP00000018835Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC103221619Histone domain-containing protein. (136 aa)
H3C11Histone H3; Belongs to the histone H3 family. (136 aa)
LOC103215048Histone domain-containing protein. (136 aa)
CENPBCentromere protein B. (603 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
ENSCSAP00000017986Histone domain-containing protein. (136 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
LOC103232262Histone H3; Belongs to the histone H3 family. (136 aa)
PABPC1L2BUncharacterized protein. (200 aa)
LOC103247786Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCSAP00000017749Small ubiquitin-related modifier. (103 aa)
TLR2Toll-like receptor. (784 aa)
CENPSCentromere protein S. (138 aa)
LCKTyrosine-protein kinase. (513 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1070 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (663 aa)
TIRAPTIR domain containing adaptor protein. (220 aa)
CD1DCD1d molecule. (337 aa)
TK1Thymidine kinase. (276 aa)
IFI16Interferon gamma inducible protein 16. (728 aa)
AIM2Absent in melanoma 2. (343 aa)
IRF3Interferon regulatory factor 3. (422 aa)
NECTIN1Nectin cell adhesion molecule 1. (519 aa)
CBLCbl proto-oncogene. (907 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
BECN1Beclin 1. (450 aa)
EIF4HEukaryotic translation initiation factor 4H. (228 aa)
DYNLT3Dynein light chain Tctex-type 3. (112 aa)
BCLAF1BCL2 associated transcription factor 1. (874 aa)
DOK2Docking protein 2. (412 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (663 aa)
TRIM23Tripartite motif containing 23. (574 aa)
CDK7Cyclin dependent kinase 7; Belongs to the protein kinase superfamily. (346 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (290 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
LMNB1Lamin B1; Belongs to the intermediate filament family. (586 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
CGASCyclic GMP-AMP synthase. (526 aa)
CDK9Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (488 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (24%) [HD]