STRINGSTRING
IFNB1 IFNB1 SMURF2 SMURF2 WWP2 WWP2 PTEN PTEN BCL6 BCL6 GAPDH GAPDH HECW2 HECW2 NEDD4 NEDD4 ITCH ITCH WWP1 WWP1 SMURF1 SMURF1 NEDD4L NEDD4L TLR3 TLR3 RPLP0 RPLP0
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFNB1Interferon beta 1. (187 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (474 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
BCL6BCL6 transcription repressor. (708 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
HECW2HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2. (1572 aa)
NEDD4E3 ubiquitin-protein ligase. (900 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
WWP1WW domain containing E3 ubiquitin protein ligase 1. (684 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (993 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
RPLP060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (279 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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