STRINGSTRING
SNCA SNCA VPS36 VPS36 LAMP1 LAMP1 PSEN2 PSEN2 VAPB VAPB MIGA2 MIGA2 PSEN1 PSEN1 VPS13C VPS13C VCP VCP MYC MYC B4GALT1 B4GALT1 RAB7A RAB7A CANX CANX ACSL3 ACSL3 VPS13A VPS13A GSK3B GSK3B POLG2 POLG2 TSG101 TSG101 PDZD8 PDZD8 RAB4B RAB4B VPS13D VPS13D MFN2 MFN2 FIS1 FIS1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNCAAlpha-synuclein; Belongs to the synuclein family. (140 aa)
VPS36Vacuolar protein sorting 36 homolog. (386 aa)
LAMP1Lysosomal associated membrane protein 1. (416 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
VAPBVAMP associated protein B and C. (243 aa)
MIGA2Mitoguardin 2. (515 aa)
PSEN1Presenilin 1. (467 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3754 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
B4GALT1Beta-1,4-galactosyltransferase 1. (398 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
CANXCalnexin. (610 aa)
ACSL3Acyl-CoA synthetase long chain family member 3. (720 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3067 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (485 aa)
TSG101Tumor susceptibility 101. (390 aa)
PDZD8PDZ domain containing 8. (1154 aa)
RAB4BUncharacterized protein. (213 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4387 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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