STRINGSTRING
SFN SFN SOX9 SOX9 CDK4 CDK4 CDK2 CDK2 GSK3B GSK3B EGF EGF NOS2 NOS2 CCND1 CCND1 MAOB MAOB MAOA MAOA MMP9 MMP9 IL10 IL10 IL1B IL1B PIK3C3 PIK3C3 XIAP XIAP MMP7 MMP7 MTOR MTOR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CDK4Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (303 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1154 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
MAOBAmine oxidase. (520 aa)
MAOAAmine oxidase. (527 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
IL10Interleukin 10. (178 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
XIAPRING-type domain-containing protein. (497 aa)
MMP7Matrix metallopeptidase 7. (270 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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