STRINGSTRING
BDNF BDNF MXRA8 MXRA8 PCSK9 PCSK9 STT3A STT3A HSP90B1 HSP90B1 GDNF GDNF LRP1B LRP1B LRP2 LRP2 VLDLR VLDLR TFRC TFRC TKFC TKFC CNTF CNTF LDLRAD3 LDLRAD3 ALB ALB EGF EGF MT-ND2 MT-ND2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (247 aa)
MXRA8Matrix remodeling associated 8. (458 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (692 aa)
STT3ASTT3 oligosaccharyltransferase complex catalytic subunit A. (705 aa)
HSP90B1Heat shock protein 90 beta family member 1. (804 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
LRP1BLDL receptor related protein 1B. (4417 aa)
LRP2LDL receptor related protein 2. (3861 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
TFRCTransferrin receptor. (774 aa)
TKFCTriokinase and FMN cyclase. (575 aa)
CNTFCiliary neurotrophic factor. (200 aa)
LDLRAD3Low density lipoprotein receptor class A domain containing 3. (345 aa)
ALBAlbumin. (512 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
MT-ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (347 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (34%) [HD]