STRINGSTRING
TBK1 TBK1 IFNG IFNG IL6 IL6 PLD2 PLD2 PLD1 PLD1 STAT1 STAT1 IRF7 IRF7 IFNAR1 IFNAR1 EOMES EOMES IFNA2 IFNA2 MX1 MX1 PXDN PXDN ISG15 ISG15 PLA2G2D PLA2G2D IFNLR1 IFNLR1 IRF3 IRF3 TLR3 TLR3 IFNGR1 IFNGR1 FRK FRK IL10 IL10 ACE2 ACE2 PXDNL PXDNL
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBK1TANK binding kinase 1. (729 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (165 aa)
IL6Interleukin 6. (212 aa)
PLD2Phospholipase. (960 aa)
PLD1Phospholipase. (1074 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
IRF7Interferon regulatory factor 7. (506 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (571 aa)
EOMESEomesodermin. (419 aa)
IFNA2Interferon alpha 2. (190 aa)
MX1MX dynamin like GTPase 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (661 aa)
PXDNPeroxidasin. (1479 aa)
ISG15ISG15 ubiquitin like modifier. (165 aa)
PLA2G2DPhospholipase A(2). (161 aa)
IFNLR1Interferon lambda receptor 1. (528 aa)
IRF3Interferon regulatory factor 3. (422 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (904 aa)
IFNGR1Interferon gamma receptor 1. (491 aa)
FRKTyrosine-protein kinase. (505 aa)
IL10Interleukin 10. (178 aa)
ACE2Angiotensin-converting enzyme. (805 aa)
PXDNLPeroxidasin like. (1336 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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