STRINGSTRING
GLIPR2 GLIPR2 RPS6KB1 RPS6KB1 ATG16L1 ATG16L1 ALDH3A1 ALDH3A1 ALDH3A2 ALDH3A2 ALDH3B1 ALDH3B1 RPS6 RPS6 NPM1 NPM1 INS INS ATG7 ATG7 MYOC MYOC ATG5 ATG5 ATG12 ATG12 GCG GCG HTT HTT NOTCH1 NOTCH1 RETREG1 RETREG1 BECN1 BECN1 MTOR MTOR ENSCSAP00000017587 ENSCSAP00000017587 SOX2 SOX2 TXN TXN ENSCSAP00000018809 ENSCSAP00000018809
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
ATG16L1Autophagy related 16 like 1. (588 aa)
ALDH3A1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (453 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
ALDH3B1Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (266 aa)
NPM1Nucleophosmin 1. (294 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa)
MYOCMyocilin. (491 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
GCGGlucagon. (180 aa)
HTTHuntingtin. (3133 aa)
NOTCH1Notch receptor 1. (2555 aa)
RETREG1Reticulophagy regulator 1. (497 aa)
BECN1Beclin 1. (450 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
ENSCSAP00000017587Thioredoxin; Belongs to the thioredoxin family. (105 aa)
SOX2SRY-box transcription factor 2. (319 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
ENSCSAP00000018809Thioredoxin; Belongs to the thioredoxin family. (102 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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