STRINGSTRING
ATF3 ATF3 TBK1 TBK1 TYRO3 TYRO3 IFNA2 IFNA2 GAPDH GAPDH STAT1 STAT1 EGR1 EGR1 AXL AXL BIRC3 BIRC3 IRF3 IRF3 OAS1 OAS1 JAK1 JAK1 IFNB1 IFNB1 SOCS1 SOCS1 SOCS3 SOCS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF3Activating transcription factor 3. (181 aa)
TBK1TANK binding kinase 1. (729 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
IFNA2Interferon alpha 2. (190 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
BIRC3Baculoviral IAP repeat containing 3. (604 aa)
IRF3Interferon regulatory factor 3. (422 aa)
OAS12'-5'-oligoadenylate synthetase 1. (448 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
IFNB1Interferon beta 1. (187 aa)
SOCS1Suppressor of cytokine signaling 1. (213 aa)
SOCS3Suppressor of cytokine signaling 3. (225 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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