STRINGSTRING
EGFR EGFR IST1 IST1 TSG101 TSG101 CD63 CD63 PLAAT3 PLAAT3 PDCD6IP PDCD6IP IFNAR1 IFNAR1 RAB5A RAB5A CD4 CD4 CD9 CD9 NCK1 NCK1 ITGB1 ITGB1 NEDD4 NEDD4 ITCH ITCH CHMP1A CHMP1A AXL AXL VPS4B VPS4B NPC1 NPC1 LAMP1 LAMP1 NCK2 NCK2 CHMP7 CHMP7 TGOLN2 TGOLN2 PTPN23 PTPN23 STAM2 STAM2 DPP4 DPP4 ATG12 ATG12 ATG5 ATG5 EPCAM EPCAM PLD2 PLD2 MAVS MAVS PLD1 PLD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGFRReceptor protein-tyrosine kinase. (1210 aa)
IST1IST1 factor associated with ESCRT-III. (364 aa)
TSG101Tumor susceptibility 101. (390 aa)
CD63Tetraspanin. (238 aa)
PLAAT3Phospholipase A and acyltransferase 3. (231 aa)
PDCD6IPBRO1 domain-containing protein. (868 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (571 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
CD4CD4 molecule. (560 aa)
CD9Tetraspanin. (228 aa)
NCK1Cytoplasmic protein. (377 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
NEDD4E3 ubiquitin-protein ligase. (900 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
VPS4BVacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (444 aa)
NPC1NPC intracellular cholesterol transporter 1. (1278 aa)
LAMP1Lysosomal associated membrane protein 1. (416 aa)
NCK2Cytoplasmic protein. (382 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
TGOLN2Trans-golgi network protein 2. (445 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1632 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
EPCAMEpithelial cell adhesion molecule. (314 aa)
PLD2Phospholipase. (960 aa)
MAVSMitochondrial antiviral signaling protein. (540 aa)
PLD1Phospholipase. (1074 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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