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ATP5F1A ATP5F1A ATG16L1 ATG16L1 ATG3 ATG3 RAB7A RAB7A RAB5A RAB5A ATG7 ATG7 ENSCSAP00000006322 ENSCSAP00000006322 GAPDH GAPDH STX17 STX17 PRKN PRKN SYNJ2BP SYNJ2BP ATG5 ATG5 ATG12 ATG12 FIS1 FIS1 CTSS CTSS MAP1LC3B MAP1LC3B ULK1 ULK1 PINK1 PINK1 TOMM20 TOMM20 RAB9A RAB9A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
ATG16L1Autophagy related 16 like 1. (588 aa)
ATG3Autophagy-related protein 3. (314 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
RAB5ARAB5A, member RAS oncogene family. (215 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa)
ENSCSAP00000006322Uncharacterized protein. (90 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (288 aa)
SYNJ2BPSynaptojanin 2 binding protein. (125 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
CTSSCathepsin S; Belongs to the peptidase C1 family. (330 aa)
MAP1LC3BUncharacterized protein. (125 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1070 aa)
PINK1PTEN induced kinase 1. (581 aa)
TOMM20Uncharacterized protein. (145 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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