STRINGSTRING
PRKCD PRKCD PRKCE PRKCE PRKCQ PRKCQ SGK2 SGK2 PRKCH PRKCH SGK3 SGK3 PKN3 PKN3 RPS6KA3 RPS6KA3 PRKX PRKX GRK4 GRK4 MAST4 MAST4 CDC42BPA CDC42BPA SGK1 SGK1 LATS1 LATS1 GRK1 GRK1 ROCK1 ROCK1 LATS2 LATS2 DMPK DMPK CIT CIT PRKCG PRKCG PKN2 PKN2 PRKACB PRKACB MAST2 MAST2 RPS6KA1 RPS6KA1 PRKCZ PRKCZ PRKACG PRKACG PRKCA PRKCA RPS6KB2 RPS6KB2 GRK2 GRK2 STK38L STK38L CDC42BPG CDC42BPG ROCK2 ROCK2 RPS6KA4 RPS6KA4 PRKG1 PRKG1 PRKCB PRKCB MAST1 MAST1 PRKACA PRKACA PKN1 PKN1 RPS6KB1 RPS6KB1 MAST3 MAST3 GRK5 GRK5 AKT2 AKT2 PRKG2 PRKG2 GRK6 GRK6 AKT3 AKT3 AKT1 AKT1 GRK3 GRK3 STK38 STK38 RPS6KA6 RPS6KA6 GRK7 GRK7 RPS6KA5 RPS6KA5 MASTL MASTL RPS6KA2 RPS6KA2 PRKCI PRKCI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (745 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (683 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
PKN3Protein kinase N3. (889 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
PRKXProtein kinase X-linked; Belongs to the protein kinase superfamily. (307 aa)
GRK4G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (572 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2430 aa)
CDC42BPANon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1873 aa)
SGK1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (431 aa)
LATS1Large tumor suppressor kinase 1. (1130 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (563 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
LATS2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (483 aa)
DMPKDM1 protein kinase. (629 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
PKN2Protein kinase N2. (983 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1802 aa)
RPS6KA1Ribosomal protein S6 kinase. (735 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (489 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1552 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
RPS6KA4Ribosomal protein S6 kinase. (772 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1570 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (354 aa)
PKN1Protein kinase N1. (944 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1139 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
AKT2Non-specific serine/threonine protein kinase. (535 aa)
PRKG2cGMP-dependent protein kinase. (675 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (576 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
GRK3G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (688 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
RPS6KA6Ribosomal protein S6 kinase. (745 aa)
GRK7G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (553 aa)
RPS6KA5Ribosomal protein S6 kinase. (776 aa)
MASTLMicrotubule associated serine/threonine kinase like. (809 aa)
RPS6KA2Ribosomal protein S6 kinase. (730 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. (482 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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