STRINGSTRING
EGF EGF LRP1 LRP1 LRP4 LRP4 LDLR LDLR LRP6 LRP6 VLDLR VLDLR LRP5 LRP5 NID1 NID1 NID2 NID2 LRP2 LRP2 ROS1 ROS1 LRP1B LRP1B SORL1 SORL1 LRP8 LRP8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
LRP1LDL receptor related protein 1. (4544 aa)
LRP4LDL receptor related protein 4. (1669 aa)
LDLRLow density lipoprotein receptor. (767 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
LRP5LDL receptor related protein 5. (1451 aa)
NID1Nidogen 1. (1249 aa)
NID2Nidogen 2. (1376 aa)
LRP2LDL receptor related protein 2. (3861 aa)
ROS1Tyrosine-protein kinase receptor. (2346 aa)
LRP1BLDL receptor related protein 1B. (4417 aa)
SORL1Sortilin related receptor 1. (2214 aa)
LRP8LDL receptor related protein 8. (1002 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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