STRINGSTRING
BRINP3 BRINP3 STAB1 STAB1 PTGS1 PTGS1 CRB2 CRB2 ITGB8 ITGB8 CRB1 CRB1 JAG1 JAG1 NRXN1 NRXN1 SCARF1 SCARF1 FBN2 FBN2 HYAL2 HYAL2 HYAL1 HYAL1 HYAL3 HYAL3 MATN4 MATN4 MEGF10 MEGF10 NRG4 NRG4 EDIL3 EDIL3 VCAN VCAN PLAT PLAT NID2 NID2 EGFL6 EGFL6 TGFA TGFA THBS4 THBS4 LRP2 LRP2 ADAM9 ADAM9 CELSR3 CELSR3 NRG1 NRG1 NOTCH1 NOTCH1 EGFL7 EGFL7 HGFAC HGFAC CSPG5 CSPG5 ADAM28 ADAM28 TDGF1 TDGF1 LRP1B LRP1B RSPO3 RSPO3 SLIT2 SLIT2 CNTNAP5 CNTNAP5 PROC PROC EGFLAM EGFLAM MFGE8 MFGE8 PROZ PROZ F7 F7 IMPG1 IMPG1 ITGBL1 ITGBL1 CFC1 CFC1 MEP1B MEP1B MUC3A MUC3A MUC17 MUC17 CCBE1 CCBE1 TENM1 TENM1 CNTNAP4 CNTNAP4 FAT4 FAT4 ADAM11 ADAM11 FAT3 FAT3 MEGF8 MEGF8 LRP1 LRP1 VWA2 VWA2 CRELD2 CRELD2 F10 F10 NID1 NID1 ATRAID ATRAID HABP2 HABP2 NELL1 NELL1 NCAN NCAN CELSR1 CELSR1 COMP COMP FBLN1 FBLN1 JAG2 JAG2 PAMR1 PAMR1 SCUBE1 SCUBE1 LRP4 LRP4 FBLN2 FBLN2 NOTCH4 NOTCH4 SNED1 SNED1 SLIT1 SLIT1 PROS1 PROS1 NOTCH3 NOTCH3 VWCE VWCE ADAM8 ADAM8 NELL2 NELL2 ENSCSAP00000003086 ENSCSAP00000003086 LDLR LDLR DNER DNER NRXN2 NRXN2 THBS1 THBS1 F9 F9 DLL4 DLL4 UMOD UMOD ITGB5 ITGB5 LRP6 LRP6 OIT3 OIT3 MUC4 MUC4 TENM3 TENM3 FAT1 FAT1 TECTA TECTA SORL1 SORL1 PEAR1 PEAR1 BCAN BCAN THBS3 THBS3 ADAM15 ADAM15 NOTCH2 NOTCH2 CELSR2 CELSR2 NTNG1 NTNG1 ADGRL4 ADGRL4 LRP8 LRP8 TIE1 TIE1 MATN1 MATN1 HSPG2 HSPG2 AGRN AGRN THBD THBD CD248 CD248 CLEC14A CLEC14A UMODL1 UMODL1 MATN3 MATN3 FBN3 FBN3 EFEMP2 EFEMP2 HEG1 HEG1 MUC13 MUC13 LTBP3 LTBP3 HHIP HHIP CNTNAP1 CNTNAP1 STAB2 STAB2 PLAU PLAU LRP5 LRP5 F12 F12 VLDLR VLDLR ENSCSAP00000005469 ENSCSAP00000005469 ADGRE1 ADGRE1 LTBP4 LTBP4 TENM4 TENM4 DLL3 DLL3 EGF EGF NPNT NPNT MMRN1 MMRN1 WIF1 WIF1 SCUBE2 SCUBE2 CLEC18C CLEC18C BTC BTC EREG EREG AREG AREG EPGN EPGN ATRNL1 ATRNL1 TEK TEK SCUBE3 SCUBE3 C1S C1S SLIT3 SLIT3 ADAM23 ADAM23 HYAL4 HYAL4 DLK1 DLK1 CRELD1 CRELD1 FBN1 FBN1 TMEM8B TMEM8B FAT2 FAT2 CD93 CD93 MSANTD3-TMEFF1 MSANTD3-TMEFF1 SELP SELP SELL SELL SELE SELE RELN RELN LTBP1 LTBP1 SVEP1 SVEP1 DLL1 DLL1 DLK2 DLK2 ASTN1 ASTN1 BRINP2 BRINP2 TMEFF2 TMEFF2 SCARF2 SCARF2 LTBP2 LTBP2 MATN2 MATN2 ADAM22 ADAM22 MEP1A MEP1A CUBN CUBN PGAP6 PGAP6 HBEGF HBEGF HMCN1 HMCN1 NRG2 NRG2 TNC TNC MEGF11 MEGF11 ADAM33 ADAM33 ATRN ATRN VWDE VWDE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BRINP3BMP/retinoic acid inducible neural specific 3. (690 aa)
STAB1Stabilin 1. (2189 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (769 aa)
CRB1Crumbs cell polarity complex component 1. (1335 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
NRXN1Neurexin 1. (831 aa)
SCARF1Scavenger receptor class F member 1. (834 aa)
FBN2Fibrillin 2. (2916 aa)
HYAL2Hyaluronidase. (473 aa)
HYAL1Hyaluronidase. (450 aa)
HYAL3Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa)
MATN4Matrilin 4. (397 aa)
MEGF10Multiple EGF like domains 10. (1140 aa)
NRG4Neuregulin 4. (117 aa)
EDIL3EGF like repeats and discoidin domains 3. (480 aa)
VCANVersican. (3394 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
NID2Nidogen 2. (1376 aa)
EGFL6EGF like domain multiple 6. (553 aa)
TGFATransforming growth factor alpha. (158 aa)
THBS4Thrombospondin 4. (870 aa)
LRP2LDL receptor related protein 2. (3861 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3317 aa)
NRG1Neuregulin 1. (467 aa)
NOTCH1Notch receptor 1. (2555 aa)
EGFL7EGF-like domain-containing protein. (384 aa)
HGFACHGF activator. (538 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (562 aa)
ADAM28ADAM metallopeptidase domain 28. (715 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa)
LRP1BLDL receptor related protein 1B. (4417 aa)
RSPO3R-spondin 3. (273 aa)
SLIT2Slit guidance ligand 2. (1332 aa)
CNTNAP5Contactin associated protein like 5. (1184 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. (547 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1009 aa)
MFGE8Milk fat globule-EGF factor 8 protein. (243 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (421 aa)
F7Coagulation factor VII. (526 aa)
IMPG1Interphotoreceptor matrix proteoglycan 1. (801 aa)
ITGBL1Integrin subunit beta like 1. (494 aa)
CFC1EGF-like domain-containing protein. (227 aa)
MEP1BMeprin A subunit. (692 aa)
MUC3AUncharacterized protein. (2174 aa)
MUC17Mucin 17, cell surface associated. (4474 aa)
CCBE1Collagen and calcium binding EGF domains 1. (336 aa)
TENM1Teneurin transmembrane protein 1. (2558 aa)
CNTNAP4Uncharacterized protein. (1308 aa)
FAT4FAT atypical cadherin 4. (4663 aa)
ADAM11ADAM metallopeptidase domain 11. (769 aa)
FAT3FAT atypical cadherin 3. (4592 aa)
MEGF8Multiple EGF like domains 8. (2789 aa)
LRP1LDL receptor related protein 1. (4544 aa)
VWA2Von Willebrand factor A domain containing 2. (757 aa)
CRELD2Cysteine rich with EGF like domains 2. (353 aa)
F10Coagulation factor X. (488 aa)
NID1Nidogen 1. (1249 aa)
ATRAIDAll-trans retinoic acid induced differentiation factor. (284 aa)
HABP2Hyaluronan binding protein 2. (560 aa)
NELL1Neural EGFL like 1. (810 aa)
NCANNeurocan. (1316 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3017 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (703 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
PAMR1Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (654 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (630 aa)
LRP4LDL receptor related protein 4. (1669 aa)
FBLN2Fibulin 2. (1225 aa)
NOTCH4Notch receptor 4. (1994 aa)
SNED1Sushi, nidogen and EGF like domains 1. (1413 aa)
SLIT1Slit guidance ligand 1. (1396 aa)
PROS1Protein S. (676 aa)
NOTCH3Notch receptor 3. (1980 aa)
VWCEVon Willebrand factor C and EGF domains. (955 aa)
ADAM8ADAM metallopeptidase domain 8. (824 aa)
NELL2Neural EGFL like 2. (868 aa)
ENSCSAP00000003086Uncharacterized protein. (1216 aa)
LDLRLow density lipoprotein receptor. (767 aa)
DNERDelta/notch like EGF repeat containing. (590 aa)
NRXN2Neurexin 2. (1582 aa)
THBS1Thrombospondin 1. (1170 aa)
F9Coagulation factor IX. (461 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
UMODUromodulin. (641 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
OIT3Oncoprotein induced transcript 3. (545 aa)
MUC4Uncharacterized protein. (2117 aa)
TENM3Teneurin transmembrane protein 3. (2427 aa)
FAT1FAT atypical cadherin 1. (4410 aa)
TECTATectorin alpha. (2158 aa)
SORL1Sortilin related receptor 1. (2214 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1037 aa)
BCANBrevican. (917 aa)
THBS3Thrombospondin 3. (947 aa)
ADAM15ADAM metallopeptidase domain 15. (754 aa)
NOTCH2Notch receptor 2. (2471 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2757 aa)
NTNG1Netrin G1. (457 aa)
ADGRL4Adhesion G protein-coupled receptor L4; Belongs to the G-protein coupled receptor 2 family. (690 aa)
LRP8LDL receptor related protein 8. (1002 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
MATN1Matrilin 1. (496 aa)
HSPG2Heparan sulfate proteoglycan 2. (4391 aa)
AGRNAgrin. (2067 aa)
THBDThrombomodulin. (626 aa)
CD248CD248 molecule. (757 aa)
CLEC14AC-type lectin domain containing 14A. (491 aa)
UMODL1Uromodulin like 1. (1318 aa)
MATN3Matrilin 3. (486 aa)
FBN3Fibrillin 3. (2776 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
HEG1Heart development protein with EGF like domains 1. (1323 aa)
MUC13Mucin 13, cell surface associated. (490 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
HHIPHedgehog interacting protein. (682 aa)
CNTNAP1Contactin associated protein 1. (1382 aa)
STAB2Stabilin 2. (2559 aa)
PLAUPlasminogen activator, urokinase. (437 aa)
LRP5LDL receptor related protein 5. (1451 aa)
F12Coagulation factor XII. (615 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
ENSCSAP00000005469Uncharacterized protein. (4096 aa)
ADGRE1Adhesion G protein-coupled receptor E1; Belongs to the G-protein coupled receptor 2 family. (908 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1557 aa)
TENM4Teneurin transmembrane protein 4. (2605 aa)
DLL3Delta like canonical Notch ligand 3. (614 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1207 aa)
NPNTNephronectin. (610 aa)
MMRN1Multimerin 1. (1224 aa)
WIF1WNT inhibitory factor 1. (379 aa)
SCUBE2Signal peptide, CUB domain and EGF like domain containing 2. (944 aa)
CLEC18CUncharacterized protein; Belongs to the CRISP family. (400 aa)
BTCBetacellulin. (171 aa)
EREGEpiregulin. (171 aa)
AREGAmphiregulin. (252 aa)
EPGNEpithelial mitogen. (154 aa)
ATRNL1Attractin like 1. (1125 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
SCUBE3Signal peptide, CUB domain and EGF like domain containing 3. (993 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (693 aa)
SLIT3Slit guidance ligand 3. (1320 aa)
ADAM23ADAM metallopeptidase domain 23. (726 aa)
HYAL4Hyaluronidase. (481 aa)
DLK1Delta like non-canonical Notch ligand 1. (310 aa)
CRELD1Cysteine rich with EGF like domains 1. (420 aa)
FBN1Fibrillin 1. (2666 aa)
TMEM8BTransmembrane protein 8B. (924 aa)
FAT2FAT atypical cadherin 2. (4349 aa)
CD93CD93 molecule. (651 aa)
MSANTD3-TMEFF1MSANTD3-TMEFF1 readthrough. (454 aa)
SELPSelectin P. (830 aa)
SELLL-selectin; Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. (385 aa)
SELESelectin E. (610 aa)
RELNReelin. (3427 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1724 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3572 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
DLK2Delta like non-canonical Notch ligand 2. (321 aa)
ASTN1Astrotactin 1. (1294 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (783 aa)
TMEFF2Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
SCARF2Scavenger receptor class F member 2. (871 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1824 aa)
MATN2Matrilin 2. (948 aa)
ADAM22ADAM metallopeptidase domain 22. (902 aa)
MEP1AMeprin A subunit. (646 aa)
CUBNCubilin. (3623 aa)
PGAP6Transmembrane protein 8A. (771 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
HMCN1Hemicentin 1. (5533 aa)
NRG2Neuregulin 2. (850 aa)
TNCTenascin C. (2201 aa)
MEGF11Multiple EGF like domains 11. (1015 aa)
ADAM33ADAM metallopeptidase domain 33. (809 aa)
ATRNAttractin. (1431 aa)
VWDEVon Willebrand factor D and EGF domains. (1573 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (22%) [HD]