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HADH HADH TPH1 TPH1 AANAT AANAT CAT CAT GCDH GCDH ECHS1 ECHS1 AOC1 AOC1 ALDH3A2 ALDH3A2 HADHA HADHA ALDH9A1 ALDH9A1 ENSCSAP00000007181 ENSCSAP00000007181 AOX1 AOX1 DLD DLD CYP1B1 CYP1B1 DLST DLST ACAT2 ACAT2 HAAO HAAO MAOB MAOB MAOA MAOA EHHADH EHHADH CYP1A1 CYP1A1 ALDH7A1 ALDH7A1 INMT INMT IDO2 IDO2 IDO1 IDO1 DDC DDC KYNU KYNU ACMSD ACMSD ALDH8A1 ALDH8A1 TDO2 TDO2 AADAT AADAT ACAT1 ACAT1 ALDH16A1 ALDH16A1 IL4I1 IL4I1 AFMID AFMID KYAT3 KYAT3 ALDH1B1 ALDH1B1
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HADHHydroxyacyl-CoA dehydrogenase. (314 aa)
TPH1Tryptophan hydroxylase 1. (343 aa)
AANATAralkylamine N-acetyltransferase. (204 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (188 aa)
AOC1Amine oxidase. (755 aa)
ALDH3A2Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (485 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
ALDH9A1Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (518 aa)
ENSCSAP00000007181Uncharacterized protein. (1351 aa)
AOX1Aldehyde oxidase 1. (1338 aa)
DLDDihydrolipoyl dehydrogenase. (538 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
ACAT2Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (373 aa)
HAAO3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (300 aa)
MAOBAmine oxidase. (520 aa)
MAOAAmine oxidase. (527 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
ALDH7A1Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family. (331 aa)
INMTUncharacterized protein. (259 aa)
IDO2Indoleamine 2,3-dioxygenase 2. (407 aa)
IDO1Indoleamine 2,3-dioxygenase 1. (401 aa)
DDCDopa decarboxylase. (480 aa)
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. (465 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
ALDH8A1Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family. (487 aa)
TDO2Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (406 aa)
AADATAminoadipate aminotransferase. (425 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (429 aa)
ALDH16A1Aldehyde dehydrogenase family 16 member A1. (802 aa)
IL4I1Amine oxidase. (588 aa)
AFMIDKynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (252 aa)
KYAT3Kynurenine aminotransferase 3. (454 aa)
ALDH1B1Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (517 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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