STRINGSTRING
CLNS1A CLNS1A EIF4E EIF4E NUP98 NUP98 NUP107 NUP107 EIF3F EIF3F XPOT XPOT DDX19A DDX19A DDX19B DDX19B EIF4G2 EIF4G2 NUP54 NUP54 SUMO2 SUMO2 NUP85 NUP85 EIF3A EIF3A POP4 POP4 NUP93 NUP93 ENSCSAP00000001539 ENSCSAP00000001539 UPF1 UPF1 PYM1 PYM1 NUP50 NUP50 AAAS AAAS EIF4B EIF4B FUS FUS RANGAP1 RANGAP1 NUP160 NUP160 EIF3C EIF3C EIF4E2 EIF4E2 RPP30 RPP30 NXF1 NXF1 FMR1 FMR1 RPP40 RPP40 EIF3G EIF3G SUMO3 SUMO3 NUP153 NUP153 EIF3D EIF3D RPP21 RPP21 EIF4EBP2 EIF4EBP2 STRAP STRAP DDX39B DDX39B NCBP2 NCBP2 LOC103224623 LOC103224623 NXT2 NXT2 ELAC2 ELAC2 NUP205 NUP205 NUP62CL NUP62CL EIF4E1B EIF4E1B EIF4A2 EIF4A2 THOC3 THOC3 NUP210 NUP210 LOC103232394 LOC103232394 THOC5 THOC5 EIF2B4 EIF2B4 SEC13 SEC13 EIF5 EIF5 THOC6 THOC6 CYFIP2 CYFIP2 GEMIN5 GEMIN5 NCBP1 NCBP1 TRNT1 TRNT1 FXR2 FXR2 EIF4A1 EIF4A1 EIF3E EIF3E UBE2I UBE2I XPO5 XPO5 THOC7 THOC7 PABPC1 PABPC1 EIF2S2 EIF2S2 RPP14 RPP14 EIF2B2 EIF2B2 GEMIN6 GEMIN6 NMD3 NMD3 POP1 POP1 NUP35 NUP35 NUP88 NUP88 FXR1 FXR1 TPR TPR EIF2S1 EIF2S1 UPF2 UPF2 EIF2B5 EIF2B5 EIF4G1 EIF4G1 NUP42 NUP42 EEF1A1 EEF1A1 PABPC1L PABPC1L GLE1 GLE1 GEMIN4 GEMIN4 NUP188 NUP188 PHAX PHAX SNUPN SNUPN EIF1AX EIF1AX XPO1 XPO1 TGS1 TGS1 NUP214 NUP214 PNN PNN RAE1 RAE1 EIF4EBP1 EIF4EBP1 TACC3 TACC3 ENSCSAP00000011744 ENSCSAP00000011744 ACIN1 ACIN1 PRMT5 PRMT5 EEF1A2 EEF1A2 PAIP1 PAIP1 EIF1B EIF1B NUP155 NUP155 RANBP2 RANBP2 EIF5B EIF5B NUP43 NUP43 UPF3A UPF3A SEH1L SEH1L THOC1 THOC1 POP7 POP7 NUP58 NUP58 ELAC1 ELAC1 SAP18 SAP18 POM121C POM121C EIF1AY EIF1AY THOC2 THOC2 UPF3B UPF3B NUP37 NUP37 EIF1 EIF1 CASC3 CASC3 KPNB1 KPNB1 POP5 POP5 ALYREF ALYREF EIF2B1 EIF2B1 RAN RAN NUP210L NUP210L RBM8A RBM8A DDX20 DDX20 NDC1 NDC1 MAGOH MAGOH EIF2B3 EIF2B3 PABPC4 PABPC4 EIF3I EIF3I SRRM1 SRRM1 EIF4G3 EIF4G3 TARDBP TARDBP RPP25L RPP25L PABPC1L2B PABPC1L2B PABPC5 PABPC5 SUMO1 SUMO1 EIF3J EIF3J NXT1 NXT1 RPP38 RPP38 POM121L2 POM121L2 GEMIN8 GEMIN8 GEMIN7 GEMIN7 NUP62 NUP62 RPP25 RPP25
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLNS1AChloride nucleotide-sensitive channel 1A. (237 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (217 aa)
NUP98Nucleoporin 98. (1800 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (925 aa)
EIF3FEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (361 aa)
XPOTExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (962 aa)
DDX19ADEAD-box helicase 19A. (478 aa)
DDX19BDEAD-box helicase 19B. (479 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (980 aa)
NUP54Nucleoporin 54. (508 aa)
SUMO2Small ubiquitin-related modifier. (95 aa)
NUP85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (656 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1225 aa)
POP4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (218 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa)
ENSCSAP00000001539RRM domain-containing protein. (298 aa)
UPF1UPF1 RNA helicase and ATPase. (1118 aa)
PYM1PYM homolog 1, exon junction complex associated factor. (195 aa)
NUP50Nucleoporin 50. (468 aa)
AAASUncharacterized protein. (229 aa)
EIF4BEukaryotic translation initiation factor 4B. (611 aa)
FUSFUS RNA binding protein. (532 aa)
RANGAP1Ran GTPase activating protein 1. (586 aa)
NUP160Nucleoporin 160. (1429 aa)
EIF3CEukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (913 aa)
EIF4E2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (236 aa)
RPP30Ribonuclease P/MRP subunit p30. (268 aa)
NXF1Nuclear RNA export factor 1. (619 aa)
FMR1Fragile X mental retardation 1. (611 aa)
RPP40Ribonuclease P/MRP subunit p40. (363 aa)
EIF3GEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa)
SUMO3Small ubiquitin-related modifier. (110 aa)
NUP153Nucleoporin 153. (1473 aa)
EIF3DEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (544 aa)
RPP21Ribonuclease P/MRP subunit p21. (154 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (120 aa)
STRAPSerine/threonine kinase receptor associated protein. (350 aa)
DDX39BDExD-box helicase 39B. (425 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (235 aa)
LOC103224623Uncharacterized protein. (148 aa)
NXT2Nuclear transport factor 2 like export factor 2. (197 aa)
ELAC2ElaC ribonuclease Z 2. (826 aa)
NUP205Nucleoporin 205. (1450 aa)
NUP62CLNucleoporin 62 C-terminal like. (184 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family. (247 aa)
EIF4A2Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family. (362 aa)
THOC3THO complex 3. (351 aa)
NUP210Nucleoporin 210. (1571 aa)
LOC103232394Uncharacterized protein. (626 aa)
THOC5THO complex 5. (694 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (523 aa)
SEC13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa)
EIF5Eukaryotic translation initiation factor 5. (431 aa)
THOC6THO complex 6. (341 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
GEMIN5Gem nuclear organelle associated protein 5. (1512 aa)
NCBP1Nuclear cap binding protein subunit 1. (790 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (434 aa)
FXR2FMR1 autosomal homolog 2. (673 aa)
EIF4A1Eukaryotic translation initiation factor 4A1; Belongs to the DEAD box helicase family. (406 aa)
EIF3EEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
XPO5Exportin 5. (1205 aa)
THOC7THO complex 7. (204 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (636 aa)
EIF2S2Eukaryotic translation initiation factor 2 subunit beta. (228 aa)
RPP14Ribonuclease P/MRP subunit p14. (71 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
GEMIN6Gem nuclear organelle associated protein 6. (167 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa)
POP1POP1 homolog, ribonuclease P/MRP subunit. (929 aa)
NUP35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa)
NUP88Nucleoporin 88. (741 aa)
FXR1FMR1 autosomal homolog 1. (648 aa)
TPRTranslocated promoter region, nuclear basket protein. (2363 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1272 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (720 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1565 aa)
NUP42Nucleoporin 42. (423 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
GLE1GLE1 RNA export mediator. (698 aa)
GEMIN4Gem nuclear organelle associated protein 4. (1058 aa)
NUP188Nucleoporin 188. (1753 aa)
PHAXPhosphorylated adaptor for RNA export. (394 aa)
SNUPNIBB domain-containing protein. (404 aa)
EIF1AXEukaryotic translation initiation factor 1A X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
XPO1Exportin 1. (1071 aa)
TGS1Trimethylguanosine synthase 1. (798 aa)
NUP214Nucleoporin 214. (2090 aa)
PNNPinin, desmosome associated protein. (721 aa)
RAE1Ribonucleic acid export 1. (368 aa)
EIF4EBP1Uncharacterized protein. (118 aa)
TACC3Transforming acidic coiled-coil containing protein 3. (839 aa)
ENSCSAP00000011744Tudor domain-containing protein. (294 aa)
ACIN1Apoptotic chromatin condensation inducer 1. (1341 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
EEF1A2Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (463 aa)
PAIP1Poly(A) binding protein interacting protein 1. (400 aa)
EIF1BEukaryotic translation initiation factor 1B. (113 aa)
NUP155Nucleoporin 155. (1080 aa)
RANBP2RAN binding protein 2. (3247 aa)
EIF5BEukaryotic translation initiation factor 5B. (1222 aa)
NUP43Nucleoporin 43. (380 aa)
UPF3AUPF3A regulator of nonsense mediated mRNA decay. (466 aa)
SEH1LSEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (421 aa)
THOC1THO complex 1. (657 aa)
POP7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences; Belongs to the histone-like Alba family. (140 aa)
NUP58Nucleoporin 58. (599 aa)
ELAC1ElaC ribonuclease Z 1. (279 aa)
SAP18Sin3A associated protein 18. (172 aa)
POM121CUncharacterized protein. (1107 aa)
EIF1AYEukaryotic translation initiation factor 1A Y-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
THOC2THO complex 2. (1593 aa)
UPF3BUPF3B regulator of nonsense mediated mRNA decay. (483 aa)
NUP37Nucleoporin 37. (326 aa)
EIF1Eukaryotic translation initiation factor 1. (77 aa)
CASC3CASC3 exon junction complex subunit. (704 aa)
KPNB1Karyopherin subunit beta 1. (876 aa)
POP5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (163 aa)
ALYREFAly/REF export factor. (264 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (305 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (152 aa)
NUP210LNucleoporin 210 like. (1792 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa)
DDX20DEAD-box helicase 20. (827 aa)
NDC1NDC1 transmembrane nucleoporin. (674 aa)
MAGOHMago homolog, exon junction complex subunit. (146 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (418 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa)
SRRM1Serine and arginine repetitive matrix 1. (587 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3. (1677 aa)
TARDBPUncharacterized protein. (414 aa)
RPP25LRibonuclease P/MRP subunit p25 like. (163 aa)
PABPC1L2BUncharacterized protein. (200 aa)
PABPC5Poly(A) binding protein cytoplasmic 5. (382 aa)
SUMO1Small ubiquitin-related modifier. (101 aa)
EIF3JEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (258 aa)
NXT1Nuclear transport factor 2 like export factor 1. (140 aa)
RPP38Ribonuclease P/MRP subunit p38. (282 aa)
POM121L2POM121 transmembrane nucleoporin like 2. (1035 aa)
GEMIN8Uncharacterized protein. (242 aa)
GEMIN7Gem nuclear organelle associated protein 7. (131 aa)
NUP62Nucleoporin 62. (521 aa)
RPP25Ribonuclease P and MRP subunit p25. (199 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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