STRINGSTRING
DLL3 DLL3 PSENEN PSENEN CTBP2 CTBP2 DTX3 DTX3 EP300 EP300 DTX4 DTX4 NOTCH3 NOTCH3 ADAM17 ADAM17 DTX3L DTX3L MFNG MFNG ATXN1 ATXN1 DLL4 DLL4 MAML1 MAML1 HES1 HES1 NOTCH4 NOTCH4 JAG2 JAG2 CREBBP CREBBP KAT2B KAT2B PTCRA PTCRA SNW1 SNW1 DLL1 DLL1 DVL2 DVL2 APH1B APH1B NUMB NUMB PSEN1 PSEN1 HEY1 HEY1 DVL3 DVL3 JAG1 JAG1 CIR1 CIR1 CTBP1 CTBP1 HDAC2 HDAC2 NOTCH1 NOTCH1 HEY2 HEY2 PSEN2 PSEN2 RBPJ RBPJ LFNG LFNG APH1A APH1A DTX2 DTX2 MAML3 MAML3 MAML2 MAML2 KAT2A KAT2A NCSTN NCSTN DTX1 DTX1 RFNG RFNG NCOR2 NCOR2 ENSCSAP00000016053 ENSCSAP00000016053 NOTCH2 NOTCH2 HEYL HEYL HDAC1 HDAC1 DVL1 DVL1 ATXN1L ATXN1L
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL3Delta like canonical Notch ligand 3. (614 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
CTBP2Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (386 aa)
DTX3Deltex E3 ubiquitin ligase 3. (347 aa)
EP300E1A binding protein p300. (2416 aa)
DTX4Deltex E3 ubiquitin ligase 4. (619 aa)
NOTCH3Notch receptor 3. (1980 aa)
ADAM17ADAM metallopeptidase domain 17. (824 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (739 aa)
MFNGBeta-1,3-N-acetylglucosaminyltransferase. (321 aa)
ATXN1Ataxin 1. (798 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
MAML1Mastermind like transcriptional coactivator 1. (790 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
NOTCH4Notch receptor 4. (1994 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1245 aa)
CREBBPCREB binding protein. (2417 aa)
KAT2BLysine acetyltransferase 2B. (675 aa)
PTCRAPre T cell antigen receptor alpha. (204 aa)
SNW1SNW domain containing 1. (536 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
DVL2Dishevelled segment polarity protein 2. (733 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
PSEN1Presenilin 1. (467 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
CIR1Corepressor interacting with RBPJ, 1. (441 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (421 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
NOTCH1Notch receptor 1. (2555 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (357 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (236 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
DTX2Deltex E3 ubiquitin ligase 2. (622 aa)
MAML3Mastermind like transcriptional coactivator 3. (982 aa)
MAML2Mastermind like transcriptional coactivator 2. (923 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
NCSTNNicastrin. (709 aa)
DTX1Deltex E3 ubiquitin ligase 1. (624 aa)
RFNGRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (205 aa)
NCOR2Nuclear receptor corepressor 2. (2521 aa)
ENSCSAP00000016053Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
NOTCH2Notch receptor 2. (2471 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
DVL1Dishevelled segment polarity protein 1. (574 aa)
ATXN1LAtaxin 1 like. (689 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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