STRINGSTRING
PLXNC1 PLXNC1 TRPC3 TRPC3 PAK1 PAK1 PAK4 PAK4 PARD6A PARD6A NFATC3 NFATC3 PPP3CA PPP3CA PRKCA PRKCA UNC5C UNC5C ILK ILK SRGAP1 SRGAP1 PLXNB2 PLXNB2 EPHA5 EPHA5 PIK3R2 PIK3R2 SEMA4G SEMA4G ROBO2 ROBO2 ROBO1 ROBO1 SLIT1 SLIT1 EPHA3 EPHA3 EPHA6 EPHA6 MAPK3 MAPK3 RND1 RND1 NGEF NGEF PTCH1 PTCH1 SHH SHH BOC BOC CDK5 CDK5 PLXNA3 PLXNA3 L1CAM L1CAM PLXNB3 PLXNB3 SSH2 SSH2 GSK3B GSK3B EPHA1 EPHA1 SEMA4D SEMA4D ROCK2 ROCK2 PAK6 PAK6 EPHB6 EPHB6 SEMA5B SEMA5B RAC2 RAC2 KRAS KRAS EPHA4 EPHA4 GDF7 GDF7 PLXNA1 PLXNA1 UNC5B UNC5B SSH3 SSH3 TRPC5 TRPC5 LIMK2 LIMK2 PPP3CB PPP3CB PAK3 PAK3 CAMK2G CAMK2G UNC5A UNC5A DPYSL5 DPYSL5 PLXNA4 PLXNA4 RAF1 RAF1 SMO SMO MYL9 MYL9 SLIT3 SLIT3 SEMA6D SEMA6D NTN1 NTN1 BMPR2 BMPR2 SEMA6B SEMA6B NTN3 NTN3 RYK RYK SRGAP3 SRGAP3 EPHB1 EPHB1 CXCL12 CXCL12 MET MET NCK1 NCK1 HRAS HRAS PIK3CB PIK3CB TRPC1 TRPC1 PARD3 PARD3 NRP1 NRP1 ITGB1 ITGB1 CAMK2A CAMK2A WNT5B WNT5B EFNB1 EFNB1 ABLIM3 ABLIM3 GNAI1 GNAI1 SEMA3C SEMA3C SEMA3E SEMA3E SEMA3A SEMA3A EFNA2 EFNA2 SEMA3D SEMA3D RGS3 RGS3 WNT5A WNT5A PIK3CA PIK3CA SEMA3G SEMA3G PAK5 PAK5 MAPK1 MAPK1 SRC SRC EPHB3 EPHB3 PLCG1 PLCG1 NEO1 NEO1 SEMA7A SEMA7A SEMA3B SEMA3B GNAI2 GNAI2 SEMA3F SEMA3F PDK1 PDK1 ABL1 ABL1 RASA1 RASA1 PPP3R1 PPP3R1 SRGAP2 SRGAP2 RHOA RHOA EFNA5 EFNA5 PARD6B PARD6B PLXNA2 PLXNA2 NFATC2 NFATC2 MYL5 MYL5 BMP7 BMP7 FYN FYN CAMK2B CAMK2B CFL2 CFL2 UNC5D UNC5D SEMA4F SEMA4F PLXNB1 PLXNB1 NFATC4 NFATC4 PIK3R1 PIK3R1 FZD3 FZD3 DPYSL2 DPYSL2 CXCR4 CXCR4 SLIT2 SLIT2 RGMA RGMA FES FES NCK2 NCK2 SEMA4B SEMA4B EPHA7 EPHA7 SEMA4C SEMA4C SEMA5A SEMA5A EFNB2 EFNB2 MYL12B MYL12B MYL12A MYL12A ROCK1 ROCK1 TRPC4 TRPC4 EPHB4 EPHB4 DCC DCC LIMK1 LIMK1 PARD6G PARD6G NTN4 NTN4 PLCG2 PLCG2 TRPC6 TRPC6 RRAS RRAS PTPN11 PTPN11 ARHGEF12 ARHGEF12 ROBO3 ROBO3 RAC3 RAC3 SEMA4A SEMA4A EFNA1 EFNA1 EFNA3 EFNA3 EFNA4 EFNA4 SEMA6C SEMA6C NRAS NRAS GNAI3 GNAI3 NTNG1 NTNG1 PIK3R3 PIK3R3 EPHB2 EPHB2 EPHA8 EPHA8 WNT4 WNT4 CDC42 CDC42 EPHA2 EPHA2 PIK3CD PIK3CD PRKCZ PRKCZ LOC103224743 LOC103224743 LRRC4 LRRC4 LRRC4C LRRC4C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLXNC1Plexin C1. (1203 aa)
TRPC3Transient receptor potential cation channel subfamily C member 3; Belongs to the transient receptor (TC 1.A.4) family. (876 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
PAK4Non-specific serine/threonine protein kinase. (633 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
NFATC3RHD domain-containing protein. (637 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
UNC5CUnc-5 netrin receptor C. (583 aa)
ILKIntegrin linked kinase. (452 aa)
SRGAP1SLIT-ROBO Rho GTPase activating protein 1. (1085 aa)
PLXNB2Plexin B2. (1844 aa)
EPHA5EPH receptor A5. (1042 aa)
PIK3R2Uncharacterized protein. (629 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (810 aa)
ROBO2Roundabout guidance receptor 2. (1235 aa)
ROBO1Uncharacterized protein. (1466 aa)
SLIT1Slit guidance ligand 1. (1396 aa)
EPHA3EPH receptor A3. (984 aa)
EPHA6Eph LBD domain-containing protein. (281 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
RND1Rho family GTPase 1. (232 aa)
NGEFNeuronal guanine nucleotide exchange factor. (713 aa)
PTCH1Patched 1. (1452 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
BOCBOC cell adhesion associated, oncogene regulated. (1115 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
PLXNA3Plexin A3. (1871 aa)
L1CAML1 cell adhesion molecule. (1257 aa)
PLXNB3Plexin B3. (1909 aa)
SSH2Slingshot protein phosphatase 2. (1430 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
EPHA1EPH receptor A1. (979 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
PAK6Non-specific serine/threonine protein kinase. (681 aa)
EPHB6EPH receptor B6. (1018 aa)
SEMA5BSemaphorin 5B. (1152 aa)
RAC2Rac family small GTPase 2. (192 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
EPHA4EPH receptor A4. (986 aa)
GDF7Growth differentiation factor 7. (447 aa)
PLXNA1Plexin A1. (1916 aa)
UNC5BUnc-5 netrin receptor B. (936 aa)
SSH3Slingshot protein phosphatase 3. (657 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
LIMK2LIM domain kinase 2. (638 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
PAK3Non-specific serine/threonine protein kinase. (559 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
UNC5AUnc-5 netrin receptor A. (797 aa)
DPYSL5Dihydropyrimidinase like 5. (563 aa)
PLXNA4Plexin A4. (1894 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
MYL9Myosin light chain 9. (172 aa)
SLIT3Slit guidance ligand 3. (1320 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1073 aa)
NTN1Netrin 1. (604 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SEMA6BSema domain-containing protein; Belongs to the semaphorin family. (374 aa)
NTN3Netrin 3. (576 aa)
RYKReceptor like tyrosine kinase. (609 aa)
SRGAP3SLIT-ROBO Rho GTPase activating protein 3. (1075 aa)
EPHB1EPH receptor B1. (984 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1381 aa)
NCK1Cytoplasmic protein. (377 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (793 aa)
PARD3Par-3 family cell polarity regulator. (1218 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
ABLIM3Actin binding LIM protein family member 3. (684 aa)
GNAI1G protein subunit alpha i1. (354 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (715 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (746 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (213 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
RGS3Regulator of G protein signaling 3. (1085 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SRCTyrosine-protein kinase. (633 aa)
EPHB3EPH receptor B3. (1001 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
NEO1Neogenin 1. (1465 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (501 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (748 aa)
GNAI2G protein subunit alpha i2. (355 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (754 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
RASA1RAS p21 protein activator 1. (1047 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
SRGAP2Uncharacterized protein. (1071 aa)
RHOARas homolog family member A. (193 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (197 aa)
PARD6BPar-6 family cell polarity regulator beta. (372 aa)
PLXNA2Plexin A2. (1909 aa)
NFATC2Nuclear factor of activated T cells 2. (928 aa)
MYL5Myosin light chain 5. (173 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
FYNTyrosine-protein kinase. (537 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
UNC5DUnc-5 netrin receptor D. (854 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
PLXNB1Plexin B1. (2140 aa)
NFATC4Nuclear factor of activated T cells 4. (901 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
DPYSL2Dihydropyrimidinase like 2. (572 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa)
SLIT2Slit guidance ligand 2. (1332 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (450 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
NCK2Cytoplasmic protein. (382 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (836 aa)
EPHA7EPH receptor A7. (989 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
SEMA5ASemaphorin 5A. (1074 aa)
EFNB2Ephrin B2; Belongs to the ephrin family. (333 aa)
MYL12BMyosin light chain 12B. (172 aa)
MYL12AMyosin light chain 12A. (171 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
TRPC4ANK_REP_REGION domain-containing protein. (395 aa)
EPHB4EPH receptor B4. (987 aa)
DCCDCC netrin 1 receptor. (1420 aa)
LIMK1LIM domain kinase 1. (647 aa)
PARD6GPB1 domain-containing protein. (133 aa)
NTN4Netrin 4. (628 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (876 aa)
RRASRAS related. (218 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
ROBO3Roundabout guidance receptor 3. (1384 aa)
RAC3Rac family small GTPase 3. (192 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (810 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (215 aa)
EFNA4Ephrin A4; Belongs to the ephrin family. (201 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (931 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
GNAI3G protein subunit alpha i3. (354 aa)
NTNG1Netrin G1. (457 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
EPHB2EPH receptor B2. (975 aa)
EPHA8EPH receptor A8. (1006 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CDC42Cell division cycle 42. (191 aa)
EPHA2EPH receptor A2. (1033 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
LOC103224743ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (166 aa)
LRRC4Leucine rich repeat containing 4. (653 aa)
LRRC4CLeucine rich repeat containing 4C. (640 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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