STRINGSTRING
AKT2 AKT2 PPP3CA PPP3CA PRKCA PRKCA MAPK11 MAPK11 KDR KDR SPHK1 SPHK1 PIK3R2 PIK3R2 MAPK3 MAPK3 PRKCB PRKCB NOS3 NOS3 BAD BAD RAC2 RAC2 KRAS KRAS PLA2G4B PLA2G4B PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F PPP3CB PPP3CB AKT3 AKT3 RAF1 RAF1 AKT1 AKT1 MAPK14 MAPK14 MAPK13 MAPK13 MAP2K2 MAP2K2 HRAS HRAS PIK3CB PIK3CB VEGFA VEGFA PIK3CA PIK3CA SHC2 SHC2 MAP2K1 MAP2K1 PTGS2 PTGS2 PLA2G4A PLA2G4A MAPK1 MAPK1 SRC SRC PLCG1 PLCG1 ENSCSAP00000010255 ENSCSAP00000010255 MAPKAPK3 MAPKAPK3 PPP3R1 PPP3R1 MAPKAPK2 MAPKAPK2 NFATC2 NFATC2 PIK3R1 PIK3R1 HSPB1 HSPB1 PLCG2 PLCG2 SPHK2 SPHK2 PXN PXN SH2D2A SH2D2A RAC3 RAC3 PRKCG PRKCG NRAS NRAS PIK3R3 PIK3R3 CDC42 CDC42 PIK3CD PIK3CD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase. (535 aa)
PPP3CASerine/threonine-protein phosphatase. (471 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SPHK1Sphingosine kinase 1. (472 aa)
PIK3R2Uncharacterized protein. (629 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
NOS3Nitric oxide synthase 3. (867 aa)
BADBCL2 associated agonist of cell death. (167 aa)
RAC2Rac family small GTPase 2. (192 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PLA2G4BPhospholipase A2. (1012 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (825 aa)
PLA2G4FPhospholipase A2. (853 aa)
PPP3CBSerine/threonine-protein phosphatase. (534 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
SHC2Uncharacterized protein. (590 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (572 aa)
PLA2G4APhospholipase A2. (749 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SRCTyrosine-protein kinase. (633 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
ENSCSAP00000010255Protein kinase domain-containing protein. (310 aa)
MAPKAPK3Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa)
PPP3R1Protein phosphatase 3 regulatory subunit B, alpha. (170 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (400 aa)
NFATC2Nuclear factor of activated T cells 2. (928 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (143 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
SPHK2Sphingosine kinase 2. (653 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (591 aa)
SH2D2ASH2 domain containing 2A. (389 aa)
RAC3Rac family small GTPase 3. (192 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
CDC42Cell division cycle 42. (191 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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