STRINGSTRING
FGF2 FGF2 WNT9B WNT9B WNT3 WNT3 AKT2 AKT2 MYF5 MYF5 AXIN2 AXIN2 ZFHX3 ZFHX3 SMARCAD1 SMARCAD1 FGFR2 FGFR2 GRB2 GRB2 INHBE INHBE INHBC INHBC MAPK11 MAPK11 REST REST PAX6 PAX6 WNT7B WNT7B PCGF6 PCGF6 PIK3R2 PIK3R2 JAK3 JAK3 WNT8B WNT8B ACVR1B ACVR1B MAPK3 MAPK3 WNT1 WNT1 WNT10B WNT10B PCGF5 PCGF5 DUSP9 DUSP9 ID2 ID2 GSK3B GSK3B ZIC3 ZIC3 JARID2 JARID2 ID4 ID4 KRAS KRAS NODAL NODAL WNT10A WNT10A WNT6 WNT6 JAK2 JAK2 FGFR4 FGFR4 ESX1 ESX1 AKT3 AKT3 WNT7A WNT7A LIF LIF RAF1 RAF1 BMPR1A BMPR1A AKT1 AKT1 NANOG NANOG MYC MYC MAPK14 MAPK14 MAPK13 MAPK13 BMPR2 BMPR2 WNT16 WNT16 MAP2K2 MAP2K2 HAND1 HAND1 WNT2 WNT2 HRAS HRAS PIK3CB PIK3CB ONECUT1 ONECUT1 WNT5B WNT5B FZD6 FZD6 DVL2 DVL2 ESRRB ESRRB TCF3 TCF3 BMI1 BMI1 SKIL SKIL ID1 ID1 HESX1 HESX1 AXIN1 AXIN1 WNT5A WNT5A PIK3CA PIK3CA DLX5 DLX5 MAP2K1 MAP2K1 WNT8A WNT8A SMAD3 SMAD3 SMAD5 SMAD5 DVL3 DVL3 MAPK1 MAPK1 HOXA1 HOXA1 HOXD1 HOXD1 ACVR2B ACVR2B OTX1 OTX1 MEIS1 MEIS1 BMP4 BMP4 APC APC KAT6A KAT6A INHBA INHBA PCGF3 PCGF3 FGFR3 FGFR3 PCGF1 PCGF1 PIK3R1 PIK3R1 FZD3 FZD3 ACVR1 ACVR1 ACVR1C ACVR1C RIF1 RIF1 ACVR2A ACVR2A IL6ST IL6ST LEFTY1 LEFTY1 LEFTY2 LEFTY2 WNT9A WNT9A WNT3A WNT3A INHBB INHBB ISL1 ISL1 CTNNB1 CTNNB1 IGF1R IGF1R LIFR LIFR SMAD9 SMAD9 SMAD2 SMAD2 SETDB1 SETDB1 SMAD4 SMAD4 RHOXF2 RHOXF2 FZD4 FZD4 SMAD1 SMAD1 IGF1 IGF1 STAT3 STAT3 PCGF2 PCGF2 HOXB1 HOXB1 LHX5 LHX5 TBX3 TBX3 NRAS NRAS WNT2B WNT2B JAK1 JAK1 PIK3R3 PIK3R3 ID3 ID3 WNT4 WNT4 PIK3CD PIK3CD DVL1 DVL1 NEUROG1 NEUROG1 APC2 APC2 FZD7 FZD7 FZD5 FZD5 SOX2 SOX2 FZD10 FZD10 NANOGP8 NANOGP8 FZD2 FZD2 FZD1 FZD1 FZD9 FZD9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (288 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
AKT2Non-specific serine/threonine protein kinase. (535 aa)
MYF5Myogenic factor 5. (255 aa)
AXIN2Axin 2. (843 aa)
ZFHX3Zinc finger homeobox 3. (3699 aa)
SMARCAD1Uncharacterized protein. (840 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
INHBEInhibin subunit beta E. (351 aa)
INHBCInhibin subunit beta C. (352 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
RESTRE1 silencing transcription factor. (1096 aa)
PAX6Paired box 6. (436 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
PCGF6Polycomb group ring finger 6. (350 aa)
PIK3R2Uncharacterized protein. (629 aa)
JAK3Tyrosine-protein kinase. (1069 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
PCGF5Polycomb group ring finger 5. (256 aa)
DUSP9Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
ZIC3Zic family member 3. (466 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
NODALNodal growth differentiation factor. (347 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
FGFR4Fibroblast growth factor receptor. (806 aa)
ESX1Homeobox domain-containing protein. (357 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
NANOGNanog homeobox. (305 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ONECUT1One cut domain family member. (241 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
DVL2Dishevelled segment polarity protein 2. (733 aa)
ESRRBEstrogen related receptor beta. (506 aa)
TCF3Transcription factor 3. (581 aa)
BMI1RING-type domain-containing protein. (449 aa)
SKILSKI like proto-oncogene. (684 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (154 aa)
HESX1HESX homeobox 1. (112 aa)
AXIN1Axin 1. (867 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
DLX5Distal-less homeobox 5. (289 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
DVL3Dishevelled segment polarity protein 3. (716 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
HOXA1Homeobox A1. (335 aa)
HOXD1Homeobox D1. (328 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
MEIS1Meis homeobox 1. (390 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
APCAPC regulator of WNT signaling pathway. (2861 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1726 aa)
INHBAInhibin subunit beta A. (426 aa)
PCGF3Polycomb group ring finger 3. (242 aa)
FGFR3Fibroblast growth factor receptor. (806 aa)
PCGF1Polycomb group ring finger 1. (259 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
RIF1Replication timing regulatory factor 1. (2465 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
LEFTY1Left-right determination factor. (366 aa)
LEFTY2Left-right determination factor. (366 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (295 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
INHBBInhibin subunit beta B. (320 aa)
ISL1ISL LIM homeobox 1. (349 aa)
CTNNB1Catenin beta 1. (781 aa)
IGF1RTyrosine-protein kinase receptor. (1064 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
SMAD9Mothers against decapentaplegic homolog. (467 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SETDB1SET domain bifurcated histone lysine methyltransferase 1. (1139 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
RHOXF2Homeobox domain-containing protein. (117 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
IGF1Insulin like growth factor 1. (159 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
HOXB1Homeobox B1. (304 aa)
LHX5LIM homeobox 5. (402 aa)
TBX3T-box transcription factor 3. (723 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (347 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
DVL1Dishevelled segment polarity protein 1. (574 aa)
NEUROG1Neurogenin 1. (237 aa)
APC2APC regulator of WNT signaling pathway 2. (1685 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (574 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
SOX2SRY-box transcription factor 2. (319 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
NANOGP8Nanog homeobox retrogene P8. (305 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (569 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (649 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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