STRINGSTRING
CFI CFI CD59 CD59 ITGAX ITGAX ZNF408 ZNF408 F2RL3 F2RL3 ITGAM ITGAM PROS1 PROS1 SERPING1 SERPING1 F8 F8 MBL2 MBL2 VTN VTN F13A1 F13A1 F9 F9 ITGB2 ITGB2 F12 F12 C2 C2 PLAU PLAU C4B C4B MASP1 MASP1 KNG1 KNG1 ENSCSAP00000005595 ENSCSAP00000005595 A2M A2M C1S C1S C1R C1R BDKRB2 BDKRB2 VWF VWF SERPINA5 SERPINA5 SERPINA1 SERPINA1 F5 F5 PROCR PROCR VSIG4 VSIG4 PLG PLG TFPI TFPI CFD CFD C5 C5 SERPIND1 SERPIND1 CFHR4 CFHR4 CFHR2 CFHR2 CFHR5 CFHR5 F13B F13B SERPINF2 SERPINF2 PLAT PLAT C4BPB C4BPB CD55 CD55 CR2 CR2 CD46 CD46 F2R F2R F2RL2 F2RL2 C6 C6 C7 C7 C9 C9 F10 F10 F7 F7 CPB2 CPB2 SERPINE1 SERPINE1 SERPINB2 SERPINB2 FGB FGB FGA FGA FGG FGG C5AR1 C5AR1 KLKB1 KLKB1 F11 F11 F3 F3 C8B C8B C8A C8A C1QB C1QB C1QC C1QC MASP2 MASP2 THBD THBD C3AR1 C3AR1 BDKRB1 BDKRB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFIComplement factor I; Belongs to the peptidase S1 family. (583 aa)
CD59UPAR/Ly6 domain-containing protein. (126 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1169 aa)
ZNF408Zinc finger protein 408. (719 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1151 aa)
PROS1Protein S. (676 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (500 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2355 aa)
MBL2Mannose binding lectin 2. (255 aa)
VTNSMB domain-containing protein. (478 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
F9Coagulation factor IX. (461 aa)
ITGB2Integrin beta. (784 aa)
F12Coagulation factor XII. (615 aa)
C2Uncharacterized protein; Belongs to the peptidase S1 family. (1266 aa)
PLAUPlasminogen activator, urokinase. (437 aa)
C4BUncharacterized protein. (1744 aa)
MASP1Mannan binding lectin serine peptidase 1. (699 aa)
KNG1Kininogen 1. (427 aa)
ENSCSAP00000005595C-type lectin domain-containing protein. (249 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (693 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (644 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (391 aa)
VWFVon Willebrand factor. (2813 aa)
SERPINA5Serpin family A member 5; Belongs to the serpin family. (355 aa)
SERPINA1Serpin family A member 1; Belongs to the serpin family. (418 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2156 aa)
PROCRProtein C receptor. (238 aa)
VSIG4V-set and immunoglobulin domain containing 4. (404 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
TFPITissue factor pathway inhibitor. (300 aa)
CFDComplement factor D; Belongs to the peptidase S1 family. (253 aa)
C5Complement C5. (1676 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
CFHR4Complement factor H related 4. (675 aa)
CFHR2Complement factor H related 2. (278 aa)
CFHR5Complement factor H related 5. (577 aa)
F13BCoagulation factor XIII B chain. (651 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (495 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (562 aa)
C4BPBComplement component 4 binding protein beta. (252 aa)
CD55CD55 molecule (Cromer blood group). (441 aa)
CR2Complement C3d receptor 2. (1093 aa)
CD46Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. (377 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
F2RL2Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
C6Complement C6. (934 aa)
C7Complement C7. (843 aa)
C9Complement C9. (561 aa)
F10Coagulation factor X. (488 aa)
F7Coagulation factor VII. (526 aa)
CPB2Carboxypeptidase B2. (423 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
SERPINB2Serpin family B member 2; Belongs to the serpin family. (415 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (875 aa)
FGGFibrinogen gamma chain. (437 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (406 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (642 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (609 aa)
F3Coagulation factor III, tissue factor. (245 aa)
C8BComplement C8 beta chain. (591 aa)
C8AComplement C8 alpha chain. (584 aa)
C1QBComplement C1q B chain. (253 aa)
C1QCComplement C1q C chain. (245 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (383 aa)
THBDThrombomodulin. (626 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (480 aa)
BDKRB1Bradykinin receptor B1. (353 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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