STRINGSTRING
AKT2 AKT2 ITGB3 ITGB3 PPP1R12A PPP1R12A GNA13 GNA13 STIM1 STIM1 RAP1B RAP1B PRKG2 PRKG2 MAPK11 MAPK11 COL1A1 COL1A1 ADCY7 ADCY7 PIK3R2 PIK3R2 MYLK3 MYLK3 ZNF408 ZNF408 F2RL3 F2RL3 MAPK3 MAPK3 ADCY6 ADCY6 NOS3 NOS3 FERMT3 FERMT3 PLCB3 PLCB3 PRKG1 PRKG1 MYLK4 MYLK4 RASGRP2 RASGRP2 RASGRP1 RASGRP1 SYK SYK ROCK2 ROCK2 PLCB2 PLCB2 ADCY5 ADCY5 MYLK MYLK ITPR2 ITPR2 GNAQ GNAQ PLA2G4B PLA2G4B PLA2G4E PLA2G4E PLA2G4D PLA2G4D TBXAS1 TBXAS1 PLA2G4F PLA2G4F ADCY3 ADCY3 PPP1CA PPP1CA SNAP23 SNAP23 AKT3 AKT3 ADCY9 ADCY9 ITPR3 ITPR3 AKT1 AKT1 BTK BTK LCP2 LCP2 ADCY8 ADCY8 MAPK14 MAPK14 MAPK13 MAPK13 PIK3R5 PIK3R5 PIK3R6 PIK3R6 TLN1 TLN1 PPP1CB PPP1CB VWF VWF ITPR1 ITPR1 TBXA2R TBXA2R PIK3CB PIK3CB PIK3CG PIK3CG ITGB1 ITGB1 GNAI1 GNAI1 APBB1IP APBB1IP TLN2 TLN2 COL3A1 COL3A1 PRKCI PRKCI MYLK2 MYLK2 COL1A2 COL1A2 PIK3CA PIK3CA GP1BA GP1BA PLA2G4A PLA2G4A PTGS1 PTGS1 P2RX1 P2RX1 PLCB1 PLCB1 PLCB4 PLCB4 MAPK1 MAPK1 SRC SRC GNAI2 GNAI2 LYN LYN RHOA RHOA F2R F2R GNAS GNAS FYN FYN ADCY1 ADCY1 ADCY4 ADCY4 PIK3R1 PIK3R1 VAMP8 VAMP8 ITGA2 ITGA2 ADCY2 ADCY2 MYL12B MYL12B MYL12A MYL12A ROCK1 ROCK1 ITGA2B ITGA2B PLCG2 PLCG2 FGB FGB FGA FGA FGG FGG GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 VASP VASP PTGIR PTGIR GUCY1A2 GUCY1A2 ARHGAP35 ARHGAP35 FCGR2A FCGR2A FCER1G FCER1G PPP1CC PPP1CC ARHGEF12 ARHGEF12 ORAI1 ORAI1 RAP1A RAP1A GNAI3 GNAI3 PRKACB PRKACB PIK3R3 PIK3R3 PIK3CD PIK3CD PRKCZ PRKCZ PRKACG PRKACG LOC103243499 LOC103243499 GP9 GP9 P2RY12 P2RY12 GP5 GP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase. (535 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (942 aa)
GNA13G protein subunit alpha 13. (377 aa)
STIM1Stromal interaction molecule 1. (684 aa)
RAP1BUncharacterized protein. (184 aa)
PRKG2cGMP-dependent protein kinase. (675 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
PIK3R2Uncharacterized protein. (629 aa)
MYLK3Myosin light chain kinase 3. (874 aa)
ZNF408Zinc finger protein 408. (719 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
NOS3Nitric oxide synthase 3. (867 aa)
FERMT3Fermitin family member 3. (663 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa)
MYLK4Myosin light chain kinase family member 4; Belongs to the protein kinase superfamily. (443 aa)
RASGRP2RAS guanyl releasing protein 2. (609 aa)
RASGRP1RAS guanyl releasing protein 1. (659 aa)
SYKTyrosine-protein kinase. (635 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
MYLKMyosin light chain kinase. (1914 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
GNAQG protein subunit alpha q. (301 aa)
PLA2G4BPhospholipase A2. (1012 aa)
PLA2G4EPhospholipase A2. (869 aa)
PLA2G4DPhospholipase A2. (825 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (534 aa)
PLA2G4FPhospholipase A2. (853 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
SNAP23Synaptosome associated protein 23. (211 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
BTKTyrosine-protein kinase. (497 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (881 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (749 aa)
TLN1Talin 1. (2558 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
VWFVon Willebrand factor. (2813 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
TBXA2RThromboxane A2 receptor. (343 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
GNAI1G protein subunit alpha i1. (354 aa)
APBB1IPAmyloid beta precursor protein binding family B member 1 interacting protein. (606 aa)
TLN2Talin 2. (2542 aa)
COL3A1Collagen type III alpha 1 chain. (878 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. (482 aa)
MYLK2Myosin light chain kinase 2. (595 aa)
COL1A2Collagen type I alpha 2 chain. (1274 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (628 aa)
PLA2G4APhospholipase A2. (749 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
SRCTyrosine-protein kinase. (633 aa)
GNAI2G protein subunit alpha i2. (355 aa)
LYNTyrosine-protein kinase. (512 aa)
RHOARas homolog family member A. (193 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
GNASUncharacterized protein. (335 aa)
FYNTyrosine-protein kinase. (537 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
MYL12BMyosin light chain 12B. (172 aa)
MYL12AMyosin light chain 12A. (171 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1039 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (875 aa)
FGGFibrinogen gamma chain. (437 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
VASPVasodilator stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
PTGIRProstaglandin I2 receptor. (387 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (497 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
FCGR2AUncharacterized protein. (317 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12. (1544 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (303 aa)
RAP1ARAP1A, member of RAS oncogene family. (184 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
GP9Glycoprotein IX platelet. (177 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
GP5Glycoprotein V platelet. (560 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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