STRINGSTRING
GABARAPL2 GABARAPL2 NFKBIB NFKBIB NFKB1 NFKB1 MAPK10 MAPK10 TBK1 TBK1 ANTXR2 ANTXR2 CXCL2 CXCL2 CXCL3 CXCL3 ENSCSAP00000001094 ENSCSAP00000001094 CXCL1 CXCL1 CXCL8 CXCL8 MAPK11 MAPK11 STAT2 STAT2 NOD2 NOD2 TRAF6 TRAF6 CHUK CHUK PYCARD PYCARD MAPK3 MAPK3 CCL5 CCL5 PKN1 PKN1 TAB1 TAB1 CCL2 CCL2 IKBKG IKBKG IRAK4 IRAK4 PLCB3 PLCB3 RIPK1 RIPK1 CASR CASR PLCB2 PLCB2 DNM1L DNM1L TRPM2 TRPM2 ITPR2 ITPR2 TXN2 TXN2 RELA RELA MAPK9 MAPK9 MCU MCU SHARPIN SHARPIN TRPV2 TRPV2 NLRP3 NLRP3 GSDMD GSDMD GABARAPL1 GABARAPL1 VDAC2 VDAC2 TP53BP1 TP53BP1 FADD FADD ITPR3 ITPR3 IFNA2 IFNA2 IFNA8 IFNA8 IFNAR2 IFNAR2 IFNAR1 IFNAR1 MEFV MEFV TRAF3 TRAF3 MAPK8 MAPK8 MAPK14 MAPK14 MAPK13 MAPK13 HSP90AA1 HSP90AA1 ANTXRL ANTXRL CASP8 CASP8 IRF7 IRF7 ITPR1 ITPR1 TRPM7 TRPM7 NLRP6 NLRP6 NAMPT NAMPT NLRC4 NLRC4 GABARAP GABARAP STAT1 STAT1 HSP90AB1 HSP90AB1 RNASEL RNASEL NLRP1 NLRP1 BCL2L1 BCL2L1 RBCK1 RBCK1 RIPK2 RIPK2 MAVS MAVS MFN1 MFN1 STING1 STING1 PRKCD PRKCD TLR4 TLR4 PLCB1 PLCB1 PLCB4 PLCB4 NEK7 NEK7 MAPK1 MAPK1 IL6 IL6 YWHAE YWHAE TAB3 TAB3 MYD88 MYD88 NOD1 NOD1 PSTPIP1 PSTPIP1 ATG5 ATG5 ATG12 ATG12 IKBKE IKBKE ANTXR1 ANTXR1 VDAC3 VDAC3 IKBKB IKBKB RHOA RHOA TRAF5 TRAF5 NFKBIA NFKBIA TANK TANK NAIP NAIP CARD9 CARD9 GPRC6A GPRC6A RIPK3 RIPK3 CAMP CAMP ERBIN ERBIN IRF9 IRF9 RNF31 RNF31 TRAF2 TRAF2 IL1B IL1B CARD6 CARD6 TNFAIP3 TNFAIP3 CTSB CTSB ENSCSAP00000013023 ENSCSAP00000013023 DEFB4B DEFB4B DEFA1 DEFA1 DEFA6 DEFA6 TAB2 TAB2 MAP3K7 MAP3K7 SUGT1 SUGT1 LOC103247087 LOC103247087 TRIP6 TRIP6 CYBB CYBB BCL2 BCL2 XIAP XIAP LOC103247085 LOC103247085 PANX1 PANX1 CASP12 CASP12 CASP4 CASP4 CASP5 CASP5 CASP1 CASP1 CARD16 CARD16 ENSCSAP00000014978 ENSCSAP00000014978 CYBA CYBA CARD8 CARD8 ENSCSAP00000015158 ENSCSAP00000015158 IL18 IL18 NLRX1 NLRX1 IRF3 IRF3 OAS1 OAS1 OAS3 OAS3 OAS2 OAS2 AIM2 AIM2 IFI16 IFI16 P2RX7 P2RX7 NLRP12 NLRP12 TXNIP TXNIP NLRP7 NLRP7 GBP7 GBP7 GBP2 GBP2 GBP1 GBP1 GBP3 GBP3 PKN2 PKN2 JAK1 JAK1 MFN2 MFN2 ENSCSAP00000017563 ENSCSAP00000017563 ENSCSAP00000017564 ENSCSAP00000017564 IFNA6 IFNA6 IFNA14 IFNA14 ENSCSAP00000017567 ENSCSAP00000017567 ENSCSAP00000017568 ENSCSAP00000017568 ENSCSAP00000017569 ENSCSAP00000017569 IFNB1 IFNB1 JUN JUN TICAM1 TICAM1 TXN TXN PYDC2 PYDC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
TBK1TANK binding kinase 1. (729 aa)
ANTXR2Anthrax toxin receptor; Belongs to the ATR family. (504 aa)
CXCL2C-X-C motif chemokine. (107 aa)
CXCL3C-X-C motif chemokine. (107 aa)
ENSCSAP00000001094C-X-C motif chemokine. (154 aa)
CXCL1C-X-C motif chemokine. (107 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
STAT2Signal transducer and activator of transcription. (851 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1036 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (538 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
PYCARDPYD and CARD domain containing. (195 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
CCL5C-C motif chemokine. (91 aa)
PKN1Protein kinase N1. (944 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (338 aa)
CCL2C-C motif chemokine. (99 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (374 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (460 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
CASRCalcium sensing receptor. (882 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
TXN2Thioredoxin 2. (166 aa)
RELARELA proto-oncogene, NF-kB subunit. (548 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
MCUMitochondrial calcium uniporter. (314 aa)
SHARPINSHANK associated RH domain interactor. (383 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (764 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
GSDMDGasdermin D. (424 aa)
GABARAPL1GABA type A receptor associated protein like 1. (117 aa)
VDAC2Voltage dependent anion channel 2. (255 aa)
TP53BP1Tumor protein p53 binding protein 1. (1977 aa)
FADDDED domain-containing protein. (189 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
IFNA2Interferon alpha 2. (190 aa)
IFNA8Interferon alpha 8. (195 aa)
IFNAR2Uncharacterized protein. (516 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (571 aa)
MEFVMEFV innate immuity regulator, pyrin. (566 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
HSP90AA1HATPase_c domain-containing protein. (387 aa)
ANTXRLANTXR like. (605 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (496 aa)
IRF7Interferon regulatory factor 7. (506 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
TRPM7Transient receptor potential cation channel subfamily M member 7. (1871 aa)
NLRP6NLR family pyrin domain containing 6. (894 aa)
NAMPTNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (491 aa)
NLRC4NLR family CARD domain containing 4. (1024 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (724 aa)
RNASELRibonuclease L. (741 aa)
NLRP1NLR family pyrin domain containing 1. (1106 aa)
BCL2L1BCL2 like 1. (233 aa)
RBCK1RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
MAVSMitochondrial antiviral signaling protein. (540 aa)
MFN1Mitofusin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
STING1Transmembrane protein 173. (379 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
IL6Interleukin 6. (212 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (240 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (712 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (416 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
ANTXR1ANTXR cell adhesion molecule 1. (564 aa)
VDAC3Voltage dependent anion channel 3. (284 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
RHOARas homolog family member A. (193 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (563 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
TANKTRAF family member associated NFKB activator. (425 aa)
NAIPNLR family apoptosis inhibitory protein. (1232 aa)
CARD9Caspase recruitment domain family member 9. (499 aa)
GPRC6AG protein-coupled receptor class C group 6 member A. (928 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (518 aa)
CAMPCathelicidin antimicrobial peptide. (173 aa)
ERBINErbb2 interacting protein. (1418 aa)
IRF9Interferon regulatory factor 9. (392 aa)
RNF31Uncharacterized protein. (905 aa)
TRAF2TNF receptor-associated factor. (449 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (237 aa)
CARD6Caspase recruitment domain family member 6. (1037 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (339 aa)
ENSCSAP00000013023Uncharacterized protein. (67 aa)
DEFB4BDEFSN domain-containing protein. (64 aa)
DEFA1DEFENSIN domain-containing protein. (96 aa)
DEFA6Defensin alpha 6. (100 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
SUGT1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (333 aa)
LOC103247087Defensin_propep domain-containing protein. (94 aa)
TRIP6Thyroid hormone receptor interactor 6. (476 aa)
CYBBCytochrome b-245 beta chain. (570 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
XIAPRING-type domain-containing protein. (497 aa)
LOC103247085DEFENSIN domain-containing protein. (94 aa)
PANX1Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
CASP12Caspase 12 (gene/pseudogene); Belongs to the peptidase C14A family. (408 aa)
CASP4Caspase 4; Belongs to the peptidase C14A family. (377 aa)
CASP5Caspase 5; Belongs to the peptidase C14A family. (325 aa)
CASP1Caspase 1; Belongs to the peptidase C14A family. (462 aa)
CARD16CARD domain-containing protein. (81 aa)
ENSCSAP00000014978Uncharacterized protein; Belongs to the peptidase C14A family. (392 aa)
CYBACytochrome b-245 alpha chain. (197 aa)
CARD8Uncharacterized protein. (444 aa)
ENSCSAP00000015158FIIND domain-containing protein. (413 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
NLRX1NLR family member X1. (972 aa)
IRF3Interferon regulatory factor 3. (422 aa)
OAS12'-5'-oligoadenylate synthetase 1. (448 aa)
OAS32'-5'-oligoadenylate synthetase 3. (688 aa)
OAS22'-5'-oligoadenylate synthetase 2. (687 aa)
AIM2Absent in melanoma 2. (343 aa)
IFI16Interferon gamma inducible protein 16. (728 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (491 aa)
NLRP12NLR family pyrin domain containing 12. (1061 aa)
TXNIPThioredoxin interacting protein. (391 aa)
NLRP7NLR family pyrin domain containing 7. (861 aa)
GBP7Guanylate binding protein 7. (462 aa)
GBP2GB1/RHD3-type G domain-containing protein. (591 aa)
GBP1Guanylate binding protein 1. (590 aa)
GBP3Guanylate binding protein 3. (490 aa)
PKN2Protein kinase N2. (983 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
ENSCSAP00000017563Uncharacterized protein. (189 aa)
ENSCSAP00000017564Uncharacterized protein. (189 aa)
IFNA6Interferon alpha 6. (189 aa)
IFNA14Interferon alpha 14. (189 aa)
ENSCSAP00000017567Uncharacterized protein. (189 aa)
ENSCSAP00000017568Uncharacterized protein. (189 aa)
ENSCSAP00000017569Uncharacterized protein. (189 aa)
IFNB1Interferon beta 1. (187 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa)
TICAM1TIR domain-containing adapter molecule 1; Involved in innate immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines. (711 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (105 aa)
PYDC2Pyrin domain containing 2. (97 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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