STRINGSTRING
AKT2 AKT2 GAB2 GAB2 PRKCA PRKCA MAPK10 MAPK10 MAP2K6 MAP2K6 GRB2 GRB2 MAPK11 MAPK11 PIK3R2 PIK3R2 MS4A2 MS4A2 MAPK3 MAPK3 INPP5D INPP5D LAT LAT SYK SYK RAC2 RAC2 MAP2K3 MAP2K3 KRAS KRAS PLA2G4B PLA2G4B MAP2K7 MAP2K7 PLA2G4E PLA2G4E MAPK9 MAPK9 PLA2G4D PLA2G4D PLA2G4F PLA2G4F ENSCSAP00000005199 ENSCSAP00000005199 ENSCSAP00000005254 ENSCSAP00000005254 ENSCSAP00000005267 ENSCSAP00000005267 ENSCSAP00000005329 ENSCSAP00000005329 MAP2K4 MAP2K4 ENSCSAP00000005377 ENSCSAP00000005377 ENSCSAP00000005390 ENSCSAP00000005390 LOC103229850 LOC103229850 VAV1 VAV1 ENSCSAP00000005509 ENSCSAP00000005509 AKT3 AKT3 RAF1 RAF1 AKT1 AKT1 BTK BTK LCP2 LCP2 MAPK8 MAPK8 MAPK14 MAPK14 MAPK13 MAPK13 ALOX5 ALOX5 MAP2K2 MAP2K2 HRAS HRAS PIK3CB PIK3CB SOS1 SOS1 PIK3CA PIK3CA MAP2K1 MAP2K1 PLA2G4A PLA2G4A MAPK1 MAPK1 IL4 IL4 IL13 IL13 IL5 IL5 CSF2 CSF2 IL3 IL3 PLCG1 PLCG1 LYN LYN SOS2 SOS2 VAV2 VAV2 FYN FYN PIK3R1 PIK3R1 ALOX5AP ALOX5AP PDPK1 PDPK1 PLCG2 PLCG2 FCER1G FCER1G FCER1A FCER1A RAC3 RAC3 NRAS NRAS VAV3 VAV3 PIK3R3 PIK3R3 PIK3CD PIK3CD ENSCSAP00000019090 ENSCSAP00000019090
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKT2Non-specific serine/threonine protein kinase. (535 aa)
GAB2GRB2 associated binding protein 2. (638 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
MAPK10Mitogen-activated protein kinase. (426 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
PIK3R2Uncharacterized protein. (629 aa)
MS4A2Membrane spanning 4-domains A2. (245 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1188 aa)
LATLinker for activation of T cells. (235 aa)
SYKTyrosine-protein kinase. (635 aa)
RAC2Rac family small GTPase 2. (192 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (347 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
PLA2G4BPhospholipase A2. (1012 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (517 aa)
PLA2G4EPhospholipase A2. (869 aa)
MAPK9Mitogen-activated protein kinase. (398 aa)
PLA2G4DPhospholipase A2. (825 aa)
PLA2G4FPhospholipase A2. (853 aa)
ENSCSAP00000005199Ig-like domain-containing protein. (190 aa)
ENSCSAP00000005254Ig-like domain-containing protein. (191 aa)
ENSCSAP00000005267Ig-like domain-containing protein. (146 aa)
ENSCSAP00000005329Ig-like domain-containing protein. (126 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (363 aa)
ENSCSAP00000005377Ig-like domain-containing protein. (139 aa)
ENSCSAP00000005390Ig-like domain-containing protein. (189 aa)
LOC103229850Ig-like domain-containing protein. (134 aa)
VAV1Vav guanine nucleotide exchange factor 1. (719 aa)
ENSCSAP00000005509Ig-like domain-containing protein. (162 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (473 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
BTKTyrosine-protein kinase. (497 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
MAP2K2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (400 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1333 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
PLA2G4APhospholipase A2. (749 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
IL13Interleukin 13. (146 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
CSF2Colony stimulating factor 2. (144 aa)
IL3Interleukin-3; Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family. (143 aa)
PLCG1Phosphoinositide phospholipase C. (974 aa)
LYNTyrosine-protein kinase. (512 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1332 aa)
VAV2Vav guanine nucleotide exchange factor 2. (896 aa)
FYNTyrosine-protein kinase. (537 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (580 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FCER1GFc fragment of IgE receptor Ig. (86 aa)
FCER1AFc fragment of IgE receptor Ia. (257 aa)
RAC3Rac family small GTPase 3. (192 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
VAV3Vav guanine nucleotide exchange factor 3. (782 aa)
PIK3R3Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
ENSCSAP00000019090Ig-like domain-containing protein. (103 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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