STRINGSTRING
RYR1 RYR1 PRKCA PRKCA PRKG2 PRKG2 GRIN2C GRIN2C GNAO1 GNAO1 ADCY7 ADCY7 CACNA1G CACNA1G PER2 PER2 CACNA1I CACNA1I MAPK3 MAPK3 ADCY6 ADCY6 PRKCB PRKCB GNG3 GNG3 PLCB3 PLCB3 PRKG1 PRKG1 PLCB2 PLCB2 ADCY5 ADCY5 GNAQ GNAQ RASD1 RASD1 KCNJ6 KCNJ6 ADCY3 ADCY3 GRIN2B GRIN2B GRIN2A GRIN2A CAMK2G CAMK2G ADCY9 ADCY9 ITPR3 ITPR3 RYR2 RYR2 ADCY8 ADCY8 CREB1 CREB1 GNB3 GNB3 PER1 PER1 GRIA1 GRIA1 ITPR1 ITPR1 ADCY10 ADCY10 ENSCSAP00000007420 ENSCSAP00000007420 CACNA1C CACNA1C GNB5 GNB5 RPS6KA5 RPS6KA5 CALM1 CALM1 GNG7 GNG7 CAMK2A CAMK2A CACNA1H CACNA1H GNAI1 GNAI1 FOS FOS GNG10 GNG10 GNG11 GNG11 GNB4 GNB4 CACNA1D CACNA1D CALML4 CALML4 PLCB1 PLCB1 PLCB4 PLCB4 MAPK1 MAPK1 GNAI2 GNAI2 ADCYAP1R1 ADCYAP1R1 GNG2 GNG2 GNAS GNAS CAMK2B CAMK2B ADCY1 ADCY1 ADCY4 ADCY4 KCNJ3 KCNJ3 GRIN1 GRIN1 ADCY2 ADCY2 GNB2 GNB2 GRIA3 GRIA3 MTNR1B MTNR1B GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 GRIA2 GRIA2 GRIA4 GRIA4 GNG8 GNG8 GUCY1A2 GUCY1A2 MTNR1A MTNR1A GRIN2D GRIN2D NOS1AP NOS1AP KCNJ9 KCNJ9 GNGT2 GNGT2 KCNJ5 KCNJ5 PRKCG PRKCG GNAI3 GNAI3 PRKACB PRKACB GNG12 GNG12 PER3 PER3 GNB1 GNB1 PRKACG PRKACG LOC103243499 LOC103243499 CALML5 CALML5 CALML3 CALML3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RYR1Ryanodine receptor 1. (4303 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (620 aa)
PRKG2cGMP-dependent protein kinase. (675 aa)
GRIN2CGlutamate ionotropic receptor NMDA type subunit 2C; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1240 aa)
GNAO1G protein subunit alpha o1. (354 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1073 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2186 aa)
PER2Period circadian regulator 2. (1254 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2234 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (671 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
PRKG1Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (471 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1185 aa)
ADCY5Adenylate cyclase 5; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (885 aa)
GNAQG protein subunit alpha q. (301 aa)
RASD1Ras related dexamethasone induced 1. (279 aa)
KCNJ6Potassium voltage-gated channel subfamily J member 6. (331 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1402 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1327 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (588 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2671 aa)
RYR2Ryanodine receptor 2. (4906 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GNB3G protein subunit beta 3. (340 aa)
PER1Period circadian regulator 1. (1292 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (811 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2758 aa)
ADCY10Adenylate cyclase 10. (1616 aa)
ENSCSAP00000007420Uncharacterized protein. (914 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
GNB5G protein subunit beta 5. (353 aa)
RPS6KA5Ribosomal protein S6 kinase. (776 aa)
CALM1Calmodulin 1; Belongs to the calmodulin family. (149 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2240 aa)
GNAI1G protein subunit alpha i1. (354 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNB4G protein subunit beta 4. (340 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
CALML4Calmodulin like 4. (194 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1115 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
GNAI2G protein subunit alpha i2. (355 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (496 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GNASUncharacterized protein. (335 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (628 aa)
ADCY1Adenylate cyclase 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1072 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
GRIN1Glutamate ionotropic receptor NMDA type subunit 1. (959 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1052 aa)
GNB2G protein subunit beta 2. (340 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
GUCY1A1Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (690 aa)
GUCY1B1Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (619 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (811 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (497 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (352 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
NOS1APPID domain-containing protein. (690 aa)
KCNJ9Potassium voltage-gated channel subfamily J member 9. (450 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (354 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PER3Period circadian regulator 3. (1182 aa)
GNB1G protein subunit beta 1. (340 aa)
PRKACGProtein kinase cAMP-activated catalytic subunit gamma; Belongs to the protein kinase superfamily. (350 aa)
LOC103243499Uncharacterized protein. (251 aa)
CALML5Calmodulin like 5. (146 aa)
CALML3Calmodulin like 3; Belongs to the calmodulin family. (149 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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